(A) T2DM: serum glucose levels during glucose tolerance test (n=6 per group). (A) T2DM: serum glucose levels during glucose tolerance test (n=6 per group).

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(A) T2DM: serum glucose levels during glucose tolerance test (n=6 per group). (A) T2DM: serum glucose levels during glucose tolerance test (n=6 per group). Two-way repeat measures ANOVA shows a significant group effect (p<0.001) and time effect (p<0.001) (p<0.051 for the group×time interaction). (B) T1DM: serum glucose levels during glucose tolerance test (n=x per group). Two-way repeat measures ANOVA shows a significant group effect (p<0.001) and time effect (p<0.001) (p<0.001 for the group×time interaction). ANOVA, analysis of variance; T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus; WT, wild-type. Yochai Birnbaum et al. BMJ Open Diab Res Care 2016;4:e000227 ©2016 by American Diabetes Association