Equipment Cost Summary

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Presentation transcript:

Equipment Cost Summary MAb Crazy Production Confused Screaming – Jarret Askin, Genevieve Frigon, Aaron Spencer, Dean Yost This is only a template. You may chose to use or not use this format. I highly recommend you use a format that works for your group. Objectives Objectives: Produce 1000kg of MAb annually Introduction MAb product is designed to treat Colon Cancer, Breast Cancer, Neovascular Glaucoma, Macular Degeneration Projected Market Share Critical to Quality Variables: Oxygen levels, pH, Temperature Equipment Cost Summary The Filters are the largest contributor of equipment cost The fan is the smallest contributor Fixed Capital Cost of $5.9 million Annual operating expense of $37 million Upstream 300 - Upstream production Stream # 28 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 125 Flow Rate (kg/batch) 204 0.1 10087 106 318 3 4 425 200 9769 1696 18 14 15 2128 182 8073 10232 Temperature (°C) 37 25 Pressure (bar) 1.2 1.0 3.0 1 Component MW (g/mol) Cells (kg/batch) - 5.E-03 2E-02 0.6 Glucose (kg/batch) 180.156 0.8 20 Media (kg/batch) 424 2120 10193 Oxygen (kg/batch) 32 21 0.4 2 2.04 17 8 10 Carbon Dioxide (kg/batch) 44.01 12 Product (kg/batch) 0.6368 19 Buffer - 6M Urea (kg/batch) 60.06 Regen - 0.1M NaOH (kg/batch) 40 Nitrogen (kg/batch) 28.02 11 13 53 Production Total Conclusion 1160 kg/yr produced Sale price $10 million/kg Annual Revenue of $11.4 billion Annual Profit of $7.4 billion Downstream Economic Analysis Recommendations Confused Screaming is giving a GO recommendation on this process A pilot plant study of the separation process We would Like to acknowledge Dr. Halpern and the rest of the UNH Chemical Engineering Department for getting us this far Acknowledgement 400 - downstream production Stream # 35 42 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 126 Flow Rate (kg/batch) 272 450 10232 21 10212 91 10343 150 10364 300 181 241 10604 10845 Temperature (°C) 25 37 Pressure (bar) 1.2 1.4 1 Component MW (g/mol) Cells (kg/batch) - Glucose (kg/batch) 180.156 20 Media (kg/batch) 10193 Oxygen (kg/batch) 32 Carbon Dioxide (kg/batch) 44.01 Product (kg/batch) 19 Buffer - 6M Urea (kg/batch) 60.06 Regen - 0.1M NaOH (kg/batch) 40 Nitrogen (kg/batch) 28.02 Production Total