Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

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Presentation transcript:

Platelet-activating factor, histamine, and tryptase levels in human anaphylaxis Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS Journal of Allergy and Clinical Immunology Volume 131, Issue 1, Pages 144-149 (January 2013) DOI: 10.1016/j.jaci.2012.08.016 Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Serum levels of PAF (A), histamine (B), and tryptase (C) as a function of the severity of the allergic reaction. Journal of Allergy and Clinical Immunology 2013 131, 144-149DOI: (10.1016/j.jaci.2012.08.016) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 The relationship between the start of the allergic reaction and the timing of the blood draw for each of PAF (A), histamine (B), and tryptase (C). Journal of Allergy and Clinical Immunology 2013 131, 144-149DOI: (10.1016/j.jaci.2012.08.016) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 The levels of PAF (A), histamine (B), and tryptase (C) are shown as a function of the etiology of anaphylaxis. A, Reactions induced by foods. B, Reactions induced by medications. C, Reactions induced by stings. D, Idiopathic reactions. Journal of Allergy and Clinical Immunology 2013 131, 144-149DOI: (10.1016/j.jaci.2012.08.016) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Serum PAF levels in patients with angioedema (A) as compared with patients with hypotension (B). Journal of Allergy and Clinical Immunology 2013 131, 144-149DOI: (10.1016/j.jaci.2012.08.016) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions