186. Long-Term Results of pCMV-vegf165 Intramuscular Gene Transfer in Patients With Chronic Lower Limb Ischemia  Ilia Y. Bozo, Roman V. Deev, Igor L.

Slides:



Advertisements
Similar presentations
Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar The.
Advertisements

Jennifer G. Cheung, Krystyna Konopka, Nejat Düzgünes
Volume 6, Issue 1, Pages (July 2002)
Patient Controlled Analgesia (PCA)
Volume 20, Issue 2, (February 2012)
414. A Novel Clinical Severity Scoring Measure in Canine X-Linked Myotubular Myopathy: Results Following Systemic AAV Gene Replacement    Molecular Therapy 
209. Use of Helicobacter pyroli Neutrophil Activating Protein (NAP) as an Immune- Modulatory Agent To Enhance the Efficacy of Oncolytic Adenovirus Therapy.
446. Gender Differences in the Osteogenic & Chondrogenic Potential of Human Muscle- Derived Stem Cells In Vitro  Alex C. Scibetta, Andrea B. Liebowitz,
Genome-editing Technologies for Gene and Cell Therapy
American Journal of Kidney Diseases 
627. Non-Invasive, Multimodal Imaging of Microvesicles with Metabolically Biotinylated, Membrane-Bound Gaussia Luciferase    Molecular Therapy  Volume.
Elizabeth Morris, Alex Scibetta, Aiping Lu, Xueqin Gao, Johnny Huard
162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo
281. Rapid Generation of Induced Pluripotent Stem Cells (iPSCs) from the Urine of a Patient with Duchenne Muscular Dystrophy    Molecular Therapy  Volume.
Direct Conversion of Skin Cells into Blood: Alchemy or Science?
Molecular Therapy  Volume 20, Pages S261-S262 (May 2012) DOI: /S (16)
Evolving Gene Therapy in Primary Immunodeficiency
Volume 20, Issue 6, Pages (June 2012)
343. Benchtop DNA Synthesizer: Oligo-Templated Polymerization (OTP)
152. The Effects of AdVEGF-B and AdVEGF-D on Angiogenesis and Arteriogenesis in a Novel Porcine Model of Percutaneous Bottleneck Stent Induced Chronic.
637. Effect of PEG Grafting Degree on Morphology and Transfection Efficiency of Polycation-g-PEG/DNA Nanoparticles    Molecular Therapy  Volume 20, (May.
John R. Martin, Christopher E. Nelson, Mukesh K
Volume 26, Issue 2, Pages (February 2018)
Volume 25, Issue 1, Pages 5-7 (January 2017)
Severe Constipation Clinical Gastroenterology and Hepatology
Chen Ling, Baozheng Li, Wenqin Ma, George Aslanidi, Arun Srivastava
Michael S. Conte, MD  Journal of Vascular Surgery 
724. Blood-Derived Endothelial Progenitor Cells Can Be Isolated With a Novel Method of Diluted Whole Blood Incubation with AMD3100-Induced Mobilization.
Stem cell therapy for human cartilage defects: a systematic review
D. Coyne  Kidney International  Volume 69, Pages S1-S3 (May 2006)
Genome-editing Technologies for Gene and Cell Therapy
Premal Lulla, Carlos A. Ramos  Molecular Therapy 
Molecular Therapy  Volume 20, (May 2012) DOI: /S (16)
Molecular Therapy  Volume 7, Issue 5, (May 2003) DOI: /S (16)
547. AAV Preparations Contain Contamination from DNA Sequences in Production Plasmids Directly Outside of the ITRs  Mark A. Brimble, Junfang Zhou, Christopher.
847. Eradication of Therapy-Resistant Human Prostate Tumors Using an Ultrasound Guided Site-Specific Cancer Terminator Virus Delivery Approach    Molecular.
611. Alpha-Dystrobrevin-3 Prevents Myopathy and Restores Diaphragm Function in the Alpha-Dystrobrevin Null Mouse  Guy L. Odom, Glen B. Banks, Marvin E.
Designer Lipids Advance Systemic siRNA Delivery
Volume 20, Issue 6, Pages (June 2012)
133. Survival with Normal Neurological Development of the Juvenile Lethal Urea Cycle Defect Arginase Deficient Mouse with AAV Gene Therapy    Molecular.
660. Bowel/Bladder Sensation and Control in Patients with Spinal Cord Injury Treated with Human Embryonic Stem Cell Therapy  Geeta Shroff  Molecular Therapy 
68. Site Specific Intra-Placental Gene Transfer Corrects Fetal Growth Restriction in a Novel Mouse Model of Placental Insufficiency (PI)    Molecular.
Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic.
521. Multiplex Genome Editing of TCR°/CD52 Genes as a Platform for “Off the Shelf” Adoptive T-Cell Immunotherapies    Molecular Therapy  Volume 22, Pages.
Jennifer G. Cheung, Krystyna Konopka, Nejat Düzgünes
Chae-lyul Limg, Yeon-Ju Lee, Sujeong Kim
405. Hindlimb and Forelimb Strength Assessment in a Canine Model of X-Linked Myotubular Myopathy Following AAV-Mediated Gene Replacement    Molecular.
Diagnosing pancreatic malignancy in the setting of chronic pancreatitis: is there room for improvement?  James J. Farrell, MD  Gastrointestinal Endoscopy 
674. Molecular, Biochemical and Biomechanical Analysis of Articular Cartilage Repaired with Genetically Modified Chondrocytes Expressing Insulin-Like.
287. Improved Outcomes Following Drug-Resistant Immunotherapy in a Human Xenograft Model of Temozolomide-Resistant Glioblastoma Multiforme  Harold T.
Molecular Therapy  Volume 18, Pages S260-S261 (May 2010) DOI: /S (16)
In This Issue Molecular Therapy Volume 16, Issue 4, (April 2008)
Volume 25, Issue 3, Pages (March 2017)
372. Targeted Mutagenesis of Ubiquitin-Binding Lysine Residues on the Adeno- Associated Virus (AAV)2 Capsid Improves Its Transduction Efficiency    Molecular.
521. AAV Immunotherapy Induces Functional Antigen Specific Regulatory T-Cells to a Neuroantigen: A Potential Treatment for MS  Brad E. Hoffman  Molecular.
483. In Vivo DMD Gene Editing in Muscles and Muscle Stem Cells of Dystrophic Mice  Mohammadsharif Tabebordbar, Kexian Zhu, Jason Cheng, Jeffrey Widrick,
Rajendra N. Mitra, Min Zheng, Zongchao Han
773. Detection of RNA Interference (RNAi) Mediated mRNA Cleavage in Fresh Injected Tumor Tissue from Patients in a Phase I Trial of pbi-shRNA™ Lipoplex.
740. Prevention of Radiation-Induced Lung Injury by Administration of Gene-Modified Mesenchymal Stem Cells    Molecular Therapy  Volume 20, Pages S285-S286.
Molecular Therapy  Volume 21, Pages S247-S248 (May 2013)
Charles A. Herzog  Kidney International 
Shigeki Yagyu, Malcolm K. Brenner
History of Oncolytic Viruses: Genesis to Genetic Engineering
Long-term prognostic factors after thrombolysis for lower limb ischemia  Monica Kuoppala, MD, Sofia Franzén, MD, Bengt Lindblad, MD, PhD, Stefan Acosta,
Physical Function in Patients with Cancer
86. A Highly Compact Epitope-Based Marker Suicide Gene for Safer and Easier Adoptive T-Cell Gene Therapy    Molecular Therapy  Volume 20, Pages S35-S36.
297. Minimally Invasive Implantation of Autologous Chondrocytes Transduced with rAAV5-IGF-I Improves Longterm Cartilage Repair in Full-Thickness Chondral.
Jingxian Feng, Jiawen Wang, Junsheng Lin, Yong Diao
Shirley Wong, Roderick A. Slavcev
624. Randomized Phase II Trial of Adjuvant Autologous Tumor Cell Vaccine (FANG™) for High Risk Stage III/IV Ovarian Cancer: Preliminary Results    Molecular.
Presentation transcript:

186. Long-Term Results of pCMV-vegf165 Intramuscular Gene Transfer in Patients With Chronic Lower Limb Ischemia  Ilia Y. Bozo, Roman V. Deev, Igor L. Plaksa, Nina D. Mzhavanadze, Yuriy V. Chervyakov, Ilia N. Staroverov, Dmitriy A. Voronov, Kalinin E. Kalinin, Artur A. Isaev  Molecular Therapy  Volume 23, Pages S74-S75 (May 2015) DOI: 10.1016/S1525-0016(16)33791-1 Copyright © 2015 The American Society of Gene & Cell Therapy Terms and Conditions

Fig. 1 Pain-free walking distance in patients of test (pCMV-vegf165) and control groups. Molecular Therapy 2015 23, S74-S75DOI: (10.1016/S1525-0016(16)33791-1) Copyright © 2015 The American Society of Gene & Cell Therapy Terms and Conditions