Plasma and Peritoneal Dialysate Levels During Daptomycin Therapy for Peritonitis  Dmytro Khadzhynov, MD, Christian Joukhadar, MD, Harm Peters, MD  American Journal of Kidney Diseases  Volume 53, Issue 5, Pages 911-912 (May 2009) DOI: 10.1053/j.ajkd.2009.02.017 Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 (A) Peritoneal dialysis fluid and (B) blood trough concentrations of daptomycin in a patient with Gram-positive peritoneal dialysis–associated peritonitis. Daptomycin was given intravenously at a dose of 5 mg/kg body weight every 48 hours (open arrows). Peritoneal dialysis fluid was collected at the end of 3 daytime 4-hour periods (2 L Physioneal® 2.27% each) and 1 overnight 12-hour dwell time (2 L Extraneal® 7.5% per day). Daptomycin concentrations were measured by using high-performance liquid chromatography.6 The patient's hospital discharge is indicated. American Journal of Kidney Diseases 2009 53, 911-912DOI: (10.1053/j.ajkd.2009.02.017) Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions