C3 Glomerulonephritis: A Rare Etiology of the Pulmonary Renal Syndrome

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C3 Glomerulonephritis: A Rare Etiology of the Pulmonary Renal Syndrome Shane A. Bobart, Sanjeev Sethi, Fernando C. Fervenza  Kidney Medicine  Volume 1, Issue 1, Pages 36-39 (January 2019) DOI: 10.1016/j.xkme.2018.12.002 Copyright © 2019 The Author(s) Terms and Conditions

Figure 1 Light microscopy findings. (A) Periodic acid–Schiff (PAS) stain shows normal glomeruli. (B) Hematoxylin and eosin stain, (C) PAS stain, and (D) Masson trichrome stain each show cellular crescents (arrows) and endocapillary proliferation. Kidney Medicine 2019 1, 36-39DOI: (10.1016/j.xkme.2018.12.002) Copyright © 2019 The Author(s) Terms and Conditions

Figure 2 (Upper panel) Immunofluorescence shows bright staining for C3 in the mesangium and capillary wall. (Lower panel) Electron microscopy findings show intramembranous, subendothelial, and mesangial electron-dense deposits. Kidney Medicine 2019 1, 36-39DOI: (10.1016/j.xkme.2018.12.002) Copyright © 2019 The Author(s) Terms and Conditions