Comparison between enhanced MR imaging and fluorescent micrograph of the median nerve.A and B, No enhancement of a healthy median nerve was found on a.

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Presentation transcript:

Comparison between enhanced MR imaging and fluorescent micrograph of the median nerve.A and B, No enhancement of a healthy median nerve was found on a gadolinium- enhanced MR image (T1-weighted SE image, 600/25 [TR/TE]). Comparison between enhanced MR imaging and fluorescent micrograph of the median nerve.A and B, No enhancement of a healthy median nerve was found on a gadolinium- enhanced MR image (T1-weighted SE image, 600/25 [TR/TE]). The median nerve showed moderate signal intensities and the signal intensity was similar to that of muscle in normal conditions (A, arrow). Evans blue albumin was limited inside the blood vessels (B, arrow), and the blood-nerve barrier was maintained as seen under fluorescent microscopy.C and D, After compression with a 30-g force, no enhancement of median nerve was found on gadolinium-enhanced MR image (T1-weighted SE image, 600/25 [TR/TE]; C, arrow); however, there was seen the limited extravasation of protein tracers around intraneural blood vessels (D, arrows).E and F, Clear enhancement was seen inside the nerve compressed by a 60-g-force clip as seen on gadolinium-enhanced MR image (T1-weighted SE image, 600/25 [TR/TE]; E, arrow). In the nerve, where enhancement was found on MR imaging, Evans blue albumin emits a bright red fluorescence, which leaked outside the blood vessels, and intraneural edema was seen under a fluorescent microscope (F, asterisk). R, radius; U, ulna. Shigeru Kobayashi et al. AJNR Am J Neuroradiol 2005;26:973-980 ©2005 by American Society of Neuroradiology