RNA and Protein Synthesis
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Essential Question What is RNA and what is the purpose of RNA?
Review DNA replication: video (0:00-2:50)
RNA Structure How are RNA & DNA different? - contains the sugar RIBOSE (hence RIBOnucleic acid) - is single stranded not double stranded - contains coded information for making proteins
RNA Structure - is like a disposable copy of DNA, is a working copy of a part of DNA - contains Uracil (U) in place of Thymine (T) - involved in protein synthesis
Types of RNA Messenger RNA (mRNA) carries copies of the instructions for assembling amino acids into proteins…they carry the message
Types of RNA Ribosomal RNA (rRNA) combine with proteins to make up ribosomes (location of protein assembly)
Types of RNA Transfer RNA (tRNA) transfers the amino acids to the ribosome to become part of the proteins
****continue video**** (2:51-4:45) Transcription – process in which part of the nucleotide sequence of DNA is copied into a complementary sequence of RNA ****continue video**** (2:51-4:45) Adenine (DNA and RNA) Cystosine (DNA and RNA) Guanine(DNA and RNA) Thymine (DNA only) Uracil (RNA only) RNA polymerase DNA RNA
The Genetic Code The “DECODER” -read from inside to outside -used to read RNA three letter “word” is called a codon each codon specifies an amino acid
The Genetic Code EXAMPLE: AGC is the codon for: SERINE
Example: DNA : GAATTAGTCCATACT codons : GAA - - - - TTA GTC CAT ACT - - - - TTA GTC CAT ACT mRNA : CUU - - - - AAU CAG GUA UGA amino acids : Leucine- Asparagine- Glutamine- Valine- Stop
You Try it! DNA : GACAAGTCCACAATC codons : GAC-AAG-TCC-ACA-ATC mRNA : CUG-UUC-AGG-UGU-UAG amino acids : Leucine-Phenylalanine-Arginine-Cysteine-Stop
Translation- decoding of a mRNA message into a polypeptide chain; occurs on ribosomes (continue video 4:46-6:56)
DNA vs. RNA - is the master plan - blueprint - sugar is Deoxyribose - sugar is Ribose made of: a sugar, phosphate, and nitrogen base - double stranded - single stranded - contains A, G, C, T - contains A, G, C, U (nucleotide) - remains in the nucleus - goes to ribosomes in the cytoplasm
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