Patient case study 2—fibrotic uILD in the setting of IPAF

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Coinvolgimento polmonare nella sclerosi sistemica Marco Matucci Cerinic Departments of Rheumatology AVC BioMedicine & Division of Rheumatology AOUC Medicine,
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PFF Teal = MAIN COLORS PFF Green = Light Green = Red = HIGHLIGHT COLORS Light Grey = Dark Grey =
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Subjects characteristics
To treat or not to treat? IPF and preserved lung function
831_ePAT CARE: Patient case Dr. Molina Dr
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Patient Demographics Referred by:
Name: Age: Sex: Presenting History Symptom progression Current status:
Kaplan–Meier survival curves of interstitial pneumonia with autoimmune features (IPAF) with usual interstitial pneumonia (UIP) pattern (on high-resolution.
Pathological alterations in idiopathic pulmonary fibrosis (IPF).
Mean changes in the Short Form-36 subscales from baseline values for combined pulmonary fibrosis and emphysema (CPFE) (n=16), and chronic obstructive pulmonary.
Changes in high-resolution computed tomography (HRCT) pattern over time. a) Idiopathic pulmonary fibrosis (IPF), increased specificity over time. Changes.
Discoidin domain receptor (DDR)2 protein was highly expressed in the lungs of patients with interstitial lung disease (ILD). Discoidin domain receptor.
ECG: electrocardiogram; PFT: pulmonary function testing; Dlco: diffusion capacity of the lung for carbon monoxide; BGA: blood gas analysis; HRCT: high-resolution.
A Case of a Patient with Idiopathic Pulmonary Fibrosis with Lung Squamous Cell Carcinoma Treated with Nivolumab  Monica Khunger, MD  Journal of Thoracic.
The relationship between body mass index (BMI) and per cent predicted forced expiratory volume in 1 s (FEV1) (A) and per cent predicted forced vital capacity.
High-resolution computed tomography (HRCT) features of interstitial lung abnormalities. a) HRCT of a 56-year-old patient whose mother died of idiopathic.
Patients with exacerbations of chronic obstructive pulmonary disease admitted to hospital according to the day of the week (A), and presenting to the emergency.
Kaplan–Meier curve for the time until the development of lung cancer in patients with idiopathic pulmonary fibrosis. Kaplan–Meier curve for the time until.
Consolidated Standards of Reporting Trials diagram
Cohort identification and exclusion.
Representative images of immunohistochemical staining of discoidin domain receptor (DDR)2 in interstitial lung disease (ILD) other than idiopathic pulmonary.
The top 25 analytes by relevant q-value differentially expressed in HIV with COPD. The top number is m/z and the bottom number is RT. Y-axis is intensity.
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Kaplan–Meier survival curves of all-cause mortality in patients with idiopathic pulmonary fibrosis (IPF). Kaplan–Meier survival curves of all-cause mortality.
Modelled mean (SEM) observed forced vital capacity (FVC) volume change from baseline (mL) over time by dose intensity (>90%, ≤90%), based on actual dose.
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Prevalence of chronic obstructive pulmonary disease (COPD) defined by different criteria by age, and place of residence. The dark grey bar represents ‘rural’
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Comparison of the serum levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients with idiopathic pulmonary.
Kaplan–Meier curves for the time until myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-positive conversion (A: MPO-ANCA, B: proteinase 3.
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Kaplan–Meier curves for the time until development of microscopic polyangiitis (MPA) (A) and for survival (B) in myeroperoxidase-antineutrophil cytoplasmic.
A) Cumulative count and b) percent cumulative use of the different pulmonary function test (PFT) measures as longitudinal outcomes for systemic sclerosis-associated.
SGRQ total scores by (A) FVC % predicted at baseline and (B) use of supplemental oxygen at baseline. SGRQ total scores by (A) FVC % predicted at baseline.
Change in forced vital capacity (FVC) % predicted (% pred) per week from baseline in the CAPACITY 004 and 006 study comparing pirfenidone (2403 mg·day−1)
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Forest plot of the a) sensitivity and b) specificity of different pulmonary function test screening algorithms for the presence of systemic sclerosis-associated.
Kaplan–Meier curves for the time until development of microscopic polyangiitis (MPA) in patients with idiopathic pulmonary fibrosis according to antineutrophil.
Receiver operating characteristic ROC curve of Lung Clearance Index (LCI)1/40, LCI1/30, LCI1/20, LCI1/10 and inverse forced expiratory volume in 1 s %
Screening test accuracy of the final risk score at a threshold of ≥2
A) Small pulmonary arteries within a fibrotic area (usual interstitial pneumonia lung). a) Small pulmonary arteries within a fibrotic area (usual interstitial.
(A) Posterioranterior (PA) chest X-ray demonstrates pneumomediastinum in the anterior and middle mediastinum extending into the cervical soft tissues.
COPD Action Plan adherence.
Procedure for the diagnosis of interstitial lung diseases.
Distribution of diffusing capacity of the lung for carbon monoxide (DLCO) among 243 scleroderma patients who underwent right heart catheterisation (RHC)
Progression in the patient’s pulmonary function tests from 2010 to a) Forced vital capacity (FVC); b) total lung capacity (TLC); c) diffusing capacity.
Prevalence of chronic obstructive pulmonary disease (COPD) defined by different criteria by region. The dark grey bar represents ‘symptom-based COPD’,
Investigation of suspected idiopathic pulmonary fibrosis: multidisciplinary team (MDT) discussion is a key component of the diagnostic pathway. Investigation.
Comparison of the serum and bronchoalveolar lavage fluid (BALF) levels of CCL21 among healthy volunteers and patients with idiopathic pulmonary fibrosis.
Chronic obstructive pulmonary disease (COPD) prevalence (postbronchodilator FEV1/FVC (forced expiratory volume in 1 s/forced vital capacity)
Subtypes of ILD in pre-MDT and post-MDT cohorts.
Diagnostic algorithm for idiopathic pulmonary fibrosis (IPF).
High-resolution computed tomography images of smoking-related interstitial lung diseases (ILDs). a) Pulmonary Langerhans cell histiocytosis, b) respiratory.
Assessment of patients with possible occupational asthma.
Comparison of total lung capacity (TLC), slow vital capacity (SVC) and carbon monoxide transfer factor (Tlco) in patients with stable interstitial lung.
Presentation transcript:

Patient case study 2—fibrotic uILD in the setting of IPAF Patient case study 2—fibrotic uILD in the setting of IPAF. CTD, connective tissue disease; DLco, diffusing capacity of the lung for carbon monoxide; FVC, forced vital capacity; HRCT, high-resolution CT; ILD, interstitial lung disease; IPAF, interstitial pne... Patient case study 2—fibrotic uILD in the setting of IPAF. CTD, connective tissue disease; DLco, diffusing capacity of the lung for carbon monoxide; FVC, forced vital capacity; HRCT, high-resolution CT; ILD, interstitial lung disease; IPAF, interstitial pneumonia with autoimmune features; IPF, idiopathic pulmonary fibrosis; MDT, multidisciplinary team; uILD, unclassifiable interstitial lung disease; UIP, usual interstitial pneumonia. Toby M Maher et al. BMJ Open Resp Res 2018;5:e000289 ©2018 by British Thoracic Society