Therapeutic and prophylactic efficacy of aminocandin (IP960) against disseminated candidiasis in mice L.K. Najvar, R. Bocanegra, N.P. Wiederhold, C.

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Therapeutic and prophylactic efficacy of aminocandin (IP960) against disseminated candidiasis in mice L.K. Najvar, R. Bocanegra, N.P. Wiederhold, C. Lambros, N. Najarian, T.F. Patterson, J.R. Graybill Clinical Microbiology and Infection Volume 14, Issue 6, Pages 595-600 (June 2008) DOI: 10.1111/j.1469-0691.2008.01994.x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Survival (a, b and c) and tissue fungal burden (d, e and f) of mice given placebo (□), aminocandin 5 mg/kg (♦), aminocandin 30 mg/kg (•), caspofungin 5 mg/kg (♦) or caspofungin 30 mg/kg as a single dose at 7 days (a and d), 10 days (b and e) and 14 days (c and f) before inoculation with Candida albicans. Clinical Microbiology and Infection 2008 14, 595-600DOI: (10.1111/j.1469-0691.2008.01994.x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions