Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study D. Goletti, S. Carrara,

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Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study D. Goletti, S. Carrara, D. Vincenti, C. Saltini, E. Busi Rizzi, V. Schininà, G. Ippolito, M. Amicosante, E. Girardi Clinical Microbiology and Infection Volume 12, Issue 6, Pages 544-550 (June 2006) DOI: 10.1111/j.1469-0691.2006.01391.x Copyright © 2006 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 IFN-γ response to RD1 selected peptides in active tuberculosis (A-TB) patients and controls. Detection of IFN-γ was by the ELISPOT assay. The highest response to (A) RD1 selected peptides, and (B) RD1 intact proteins in terms of specific interferon (IFN)-γ-secreting T-cells is reported as spot-forming cells (SFCs) per million peripheral blood mononuclear cells (PBMCs) for each individual. Horizontal bars represent the mean of the SFCs for each group of patients. p values denote the difference among the responders in each group of patients. Clinical Microbiology and Infection 2006 12, 544-550DOI: (10.1111/j.1469-0691.2006.01391.x) Copyright © 2006 European Society of Clinical Infectious Diseases Terms and Conditions