Diffusion-weighted MR imaging of non-complicated hepatic cysts: Value of 3T computed diffusion-weighted imaging Yuko Nakamura, Toru Higaki, Yuji Akiyama,

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Diffusion-weighted MR imaging of non-complicated hepatic cysts: Value of 3T computed diffusion-weighted imaging Yuko Nakamura, Toru Higaki, Yuji Akiyama, Wataru Fukumoto, Kenji Kajiwara, Yoko Kaichi, Yukiko Honda, Daisuke Komoto, Fuminari Tatsugami, Makoto Iida, Toshifumi Ohmoto, Shuji Date, Kazuo Awai European Journal of Radiology Open Volume 3, Pages 138-144 (January 2016) DOI: 10.1016/j.ejro.2016.07.001 Copyright © 2016 The Author(s) Terms and Conditions

Fig. 1 Schema of the c-DWI procedure. European Journal of Radiology Open 2016 3, 138-144DOI: (10.1016/j.ejro.2016.07.001) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 2 Hepatic cyst in an 80-year-old man. (A) o-1.5T-1000-, (B) o-3T-1000-, (C) c-1000-, (D) c-1500 DWIs. The cyst (arrow) was isointense on o1.5T-1000-, showed mild high signal intensity on o-3T-1000- and c-1000-, and was isointense on c-1500 DWI. European Journal of Radiology Open 2016 3, 138-144DOI: (10.1016/j.ejro.2016.07.001) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 3 Contrast ratio (CR) of non-complicated hepatic cysts on o-1.5T-1000-, o-3T-1000-, c-1000-, and c-1500 DWIs. The solid line indicates the mean CR value in each group. The CR was higher on o-3T-1000- than on o-1.5T-1000 DWI (p<0.01). No significant difference was found between o-1.5T-1000- and c-1000 images (p=0.07). There was no significant difference between o-1.5T-1000- and c-1500 DWIs (p=0.96). European Journal of Radiology Open 2016 3, 138-144DOI: (10.1016/j.ejro.2016.07.001) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 4 Contrast ratio (CR) of non-complicated hepatic cysts smaller than 20mm on o-1.5T-1000-, o-3T-1000-, c-1000-, and c-1500 DWIs. The solid line indicates the mean CR value in each group. The CR was higher on o-3T-1000- than on o-1.5T-1000 DWI (p=0.03). No significant difference was found between o-1.5T-1000- and c-1000 images (p=0.22). The difference between o-1.5T-1000- and c-1500 images was not significant (p=0.86). European Journal of Radiology Open 2016 3, 138-144DOI: (10.1016/j.ejro.2016.07.001) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 5 Contrast ratio (CR) of non-complicated hepatic cysts larger than 20mm on o-1.5T-1000-, o-3T-1000-, c-1000-, and c-1500 DWIs. The solid line indicates the mean CR value in each group. The CR on o-3T-1000- tended to be higher compared to that on o-1.5T-1000 DWIs, but not significant (p=0.08). The CR was significantly higher on c-1000- than o-1.5T-1000 DWIs (p=0.04). The difference between o-1.5T-1000- and c-1500 images was not significant (p=1.00). European Journal of Radiology Open 2016 3, 138-144DOI: (10.1016/j.ejro.2016.07.001) Copyright © 2016 The Author(s) Terms and Conditions

Fig. 6 Contrast ratio of non-complicated hepatic cysts on images obtained with b=0s/mm2 at 1.5T and 3T (TE=60 and 70ms). The solid line indicates the mean CR value in each group. The CR was higher on 3T images with TE 70ms and 60ms than on 1.5T DWIs (p<0.01) and significantly lower on 3T scans with TE 60ms than TE 70ms (p=0.04). European Journal of Radiology Open 2016 3, 138-144DOI: (10.1016/j.ejro.2016.07.001) Copyright © 2016 The Author(s) Terms and Conditions