Time-lapse imaging reveals differences in growth dynamics of embryos after in vitro maturation compared with conventional stimulation Sabine Roesner, M.D., Jens Erik Dietrich, Ph.D., Julia Weigert, Markus Montag, Ph.D., Bettina Toth, M.D., Thomas Strowitzki, M.D. Fertility and Sterility Volume 107, Issue 3, Pages 606-612.e3 (March 2017) DOI: 10.1016/j.fertnstert.2016.12.026 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Study population and recruitment of the embryos selected for time-lapse imaging. cryo = cryopreserved; ET = embryo transfer; GQE = good-quality embryos; IVM = in vitro maturation; MII = metaphase II; PCOS = polycystic ovary syndrome; *Two embryos were not cultured in the Embryoscope. Fertility and Sterility 2017 107, 606-612.e3DOI: (10.1016/j.fertnstert.2016.12.026) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions
Figure 2 Differences in morphokinetics assessed by time-lapse imaging within the study population. (A) Box plots depicting morphokinetic times (in hours after insemination [hpi]). (B) Box plots depicting morphokinetic durations (in hours). White: in vitro maturation with polycystic ovary syndrome (PCOS); light gray: non-PCOS control; dark gray: PCOS control. Significant differences (P<.05) are indicated between the marked groups. Fertility and Sterility 2017 107, 606-612.e3DOI: (10.1016/j.fertnstert.2016.12.026) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions