Time-lapse imaging reveals differences in growth dynamics of embryos after in vitro maturation compared with conventional stimulation  Sabine Roesner,

Slides:



Advertisements
Similar presentations
Validation of a prediction model for the follicle-stimulating hormone response dose in women with polycystic ovary syndrome  Madelon van Wely, Ph.D.,
Advertisements

A review and meta-analysis of prospective trials comparing different catheters used for embryo transfer  William M. Buckett, M.D.  Fertility and Sterility 
Clinically significant and sustained weight loss is achievable in obese women with polycystic ovary syndrome followed in a regular medical practice  Lysanne.
Clinical outcome of non–hCG-primed oocyte in vitro maturation treatment in patients with polycystic ovaries and polycystic ovary syndrome  Michel De Vos,
Wendy S. Vitek, M. D. , Jeannine Witmyer, Ph. D. , Sandra A. Carson, M
Study of nucleation status in the second cell cycle of human embryo and its impact on implantation rate  Jesus Aguilar, Ph.D., Irene Rubio, Ph.D., Elkin.
Gaps in knowledge among physicians regarding diagnostic criteria and management of polycystic ovary syndrome  Anuja Dokras, M.D., Ph.D., Shailly Saini,
Increased prevalence of anxiety symptoms in women with polycystic ovary syndrome: systematic review and meta-analysis  Anuja Dokras, M.D., Ph.D., Shari.
Developmental capacity of in vitro–matured human oocytes retrieved from polycystic ovary syndrome ovaries containing no follicles larger than 6 mm  Luis.
Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis  Héctor F. Escobar-Morreale, M.D., Ph.D., Manuel Luque-Ramírez,
MRNA expression pattern of insulin-like growth factor components of granulosa cells and cumulus cells in women with and without polycystic ovary syndrome.
Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women  Babak Mokhlesi, M.D.,
Successful delivery after the transfer of embryos obtained from a cohort of incompletely in vivo matured oocytes at retrieval time  Patricia Fauque, M.D.,
Michal Youngster, M. D. , Valerie L. Ward, M. D. , M. P. H. , Emily A
Adherence compounds in embryo transfer media for assisted reproductive technologies: summary of a Cochrane review  Stephan Bontekoe, M.D., Neil Johnson,
Gaps in knowledge among physicians regarding diagnostic criteria and management of polycystic ovary syndrome  Anuja Dokras, M.D., Ph.D., Shailly Saini,
Zhi-Yong Yang, M.D., Ri-Cheng Chian, Ph.D.  Fertility and Sterility 
Progression to impaired glucose tolerance or type 2 diabetes mellitus in polycystic ovary syndrome: a controlled follow-up study  Cem Celik, M.D., Nicel.
Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) in IVF patients with polycystic ovary syndrome: correlations with outcome 
Can an educational DVD improve the acceptability of elective single embryo transfer? A randomized controlled study  Nicole Hope, M.B., B.S., Hon., Luk.
Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study  Angela Kerchner, B.A., Whitney Lester,
Robert A. Wild, M. D. , Manfredi Rizzo, M. D. , Sheri Clifton, Ph. D
Is the addition of metformin efficacious in the treatment of clomiphene citrate-resistant patients with polycystic ovary syndrome? A structured literature.
The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society.
Live birth of twins derived from zona-free oocytes
Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary.
Rebecca A. Feldman, M. D. , Kathleen O'Neill, M. D. , Samantha F
Iris G. Insogna, M. D. , Malinda S. Lee, M. D. , M. B. A. , Rebecca M
Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization  Ginny Mounce,
Does the addition of time-lapse morphokinetics in the selection of embryos for transfer improve pregnancy rates? A randomized controlled trial  Linnea.
Functional neuroimaging of emotional processing in women with polycystic ovary syndrome: a case-control pilot study  Courtney A. Marsh, M.D., M.P.H.,
Oocyte cryopreservation
Evolutionary determinants of polycystic ovary syndrome: part 1
Effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization: a systematic review and meta-analysis  Cui Hong Zheng, M.D., Ph.D.,
Influence of acupuncture stimulation on pregnancy rates for women undergoing embryo transfer  Caroline Smith, Ph.D., Meaghan Coyle, B.Hlth.Sc. (Acup.),
Andrew C. Bjonnes, M.S., Richa Saxena, Ph.D., Corrine K. Welt, M.D. 
Quintuplets after a transfer of two embryos following in vitro fertilization: a proved superfecundation  Maëliss Peigné, M.D., Joris Andrieux, M.D., Ph.D.,
Polar body biopsy Fertility and Sterility
Hyperglycemia Stimulates Activation of Nuclear Factor κB (NFκB) in Mononuclear Cells (MNC) of Women With Polycystic Ovary Syndrome (PCOS)  F. Gonzalez,
Ovulation induction in women with polycystic ovary syndrome
Should embryos developing to blastocysts on day 7 be cryopreserved and transferred: an analysis of pregnancy and implantation rates  George Kovalevsky,
Akanksha Mehta, M.D., Darius A. Paduch, M.D., Ph.D. 
Increased secretion of amylin in women with polycystic ovary syndrome
Alice A. Chen, Ph. D. , Lei Tan, Ph. D. , Vaishali Suraj, M. S
Prevalence of polycystic ovary syndrome in adolescents
Successful elective and medically indicated oocyte vitrification and warming for autologous in vitro fertilization, with predicted birth probabilities.
Comparison of the efficacy of two commercially available media for culturing one-cell embryos in the in vitro fertilization mouse model  Paulo Marcelo.
Fleur R. Cattrall, M. B. B. S. , Beverley J. Vollenhoven, M. B. B. S
Ri-Cheng Chian, Ph.D., Peter S. Uzelac, M.D., Geeta Nargund, M.D. 
Metformin treatment before and during in vitro fertilization or intracytoplasmic sperm injection in women with polycystic ovary syndrome: summary of a.
Metformin reduces serum müllerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment  Richard Fleming, Ph.D.,
Banu Ucar, M. D. , Volkan Noyan, M. D. , Osman Caglayan, M. D
Simvastatin improves biochemical parameters in women with polycystic ovary syndrome: results of a prospective, randomized trial  Antoni J. Duleba, M.D.,
S. Samuel Kim, M.D.  Fertility and Sterility 
Impact of laparoscopic ovarian drilling on anti-Müllerian hormone levels and ovarian stromal blood flow using three-dimensional power Doppler in women.
Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin  Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.
János Urbancsek, M. D. , Ph. D. , Erik E. Hauzman, M. D. , Ana R
Paolo Moghetti, M.D.  Fertility and Sterility 
Validation of a prediction model for the follicle-stimulating hormone response dose in women with polycystic ovary syndrome  Madelon van Wely, Ph.D.,
Failed IVF cycles and the risk of subsequent preeclampsia or fetal growth restriction: a case-control exploratory study  Ioanna Tsoumpou, M.D., Ahmed.
Increased acylation-stimulating protein, C-reactive protein, and lipid levels in young women with polycystic ovary syndrome  Yuwen Wu, M.D., Jianhua Zhang,
A review and meta-analysis of prospective trials comparing different catheters used for embryo transfer  William M. Buckett, M.D.  Fertility and Sterility 
Inappropriate gonadotropin secretion in polycystic ovary syndrome
Tsan-Hon Liou, M. D. , Ph. D. , Jen-Hung Yang, M. D. , Ph. D
David H. Barad, M.D., M.S., Norbert Gleicher, M.D. 
In vitro sildenafil citrate use as a sperm motility stimulant
Transforming growth factor-β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation  Reshef.
Adiponectin levels reflect the different phenotypes of polycystic ovary syndrome: study in normal weight, normoinsulinemic patients  Artemis Karkanaki,
Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization  Ginny Mounce,
Low body mass index compromises live birth rate in fresh transfer in vitro fertilization cycles: a retrospective study in a Chinese population  Jiali.
Presentation transcript:

Time-lapse imaging reveals differences in growth dynamics of embryos after in vitro maturation compared with conventional stimulation  Sabine Roesner, M.D., Jens Erik Dietrich, Ph.D., Julia Weigert, Markus Montag, Ph.D., Bettina Toth, M.D., Thomas Strowitzki, M.D.  Fertility and Sterility  Volume 107, Issue 3, Pages 606-612.e3 (March 2017) DOI: 10.1016/j.fertnstert.2016.12.026 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Study population and recruitment of the embryos selected for time-lapse imaging. cryo = cryopreserved; ET = embryo transfer; GQE = good-quality embryos; IVM = in vitro maturation; MII = metaphase II; PCOS = polycystic ovary syndrome; *Two embryos were not cultured in the Embryoscope. Fertility and Sterility 2017 107, 606-612.e3DOI: (10.1016/j.fertnstert.2016.12.026) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Differences in morphokinetics assessed by time-lapse imaging within the study population. (A) Box plots depicting morphokinetic times (in hours after insemination [hpi]). (B) Box plots depicting morphokinetic durations (in hours). White: in vitro maturation with polycystic ovary syndrome (PCOS); light gray: non-PCOS control; dark gray: PCOS control. Significant differences (P<.05) are indicated between the marked groups. Fertility and Sterility 2017 107, 606-612.e3DOI: (10.1016/j.fertnstert.2016.12.026) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions