Optimal Dosing Frequency of Pegylated Interferon Alfa-2b Monotherapy for Chronic Hepatitis C Virus Infection  Yoav Lurie, Regine Rouzier-Panis, George.

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Optimal Dosing Frequency of Pegylated Interferon Alfa-2b Monotherapy for Chronic Hepatitis C Virus Infection  Yoav Lurie, Regine Rouzier-Panis, George J.M. Webster, Geoffrey M. Dusheiko, Mark Laughlin, Mary L. Jackson, Ran Oren  Clinical Gastroenterology and Hepatology  Volume 3, Issue 6, Pages 610-615 (June 2005) DOI: 10.1016/S1542-3565(04)00723-2 Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 1 Effect of PEG-IFN-alfa2b dosage on HCV-RNA clearance at week 12. Bars are mean values with standard error (*#x002A;P < .05 vs IFN-alfa2b). BIW, 2 times/wk; QW, 1 time/wk; TIW, 3 times/wk. Clinical Gastroenterology and Hepatology 2005 3, 610-615DOI: (10.1016/S1542-3565(04)00723-2) Copyright © 2005 American Gastroenterological Association Terms and Conditions

Figure 2 Decrease in absolute neutrophil count (109 cells/L) by dose regimen, from treatment initiation through week 12. BIW, 2 times/wk; QW, 1 time/wk; TIW, 3 times/wk. Clinical Gastroenterology and Hepatology 2005 3, 610-615DOI: (10.1016/S1542-3565(04)00723-2) Copyright © 2005 American Gastroenterological Association Terms and Conditions