Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteries

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Presentation transcript:

Production of proinflammatory cytokines and myocardial dysfunction after arterial switch operation in neonates with transposition of the great arteries Hedwig H. Hövels-Gürich, MD, Jaime F. Vazquez-Jimenez, MD, Anna Silvestri, Kathrin Schumacher, Ralf Minkenberg, Jean Duchateau, MD, Bruno J. Messmer, MD, Götz von Bernuth, MD, Marie-Christine Seghaye, MD The Journal of Thoracic and Cardiovascular Surgery Volume 124, Issue 4, Pages 811-820 (October 2002) DOI: 10.1067/mtc.2002.122308 Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 1 Concentrations of cTnT related to presence (white bars, n = 11) and absence (shaded bars, n = 52) of myocardial dysfunction after CPB in 63 patients. Values expressed as mean (data points), median (horizontal lines), interquartile ranges (bars), and 10th and 90th percentiles (error bars). P values represent differences between subgroups with and without myocardial dysfunction. The Journal of Thoracic and Cardiovascular Surgery 2002 124, 811-820DOI: (10.1067/mtc.2002.122308) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 2 Correlations between cTnT values at end of CPB with those 4 (squares, Spearman correlation coefficient 0.71, P <.001) and 24 (triangles, Spearman correlation coefficient 0.60, P <.001) hours after operation in 63 patients. All parameters are expressed by their logarithmic values. The Journal of Thoracic and Cardiovascular Surgery 2002 124, 811-820DOI: (10.1067/mtc.2002.122308) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 3 IL-6 levels related to presence (white bars, n = 11) and absence (shaded bars, n = 52) of myocardial dysfunction after CPB in 63 patients. Values expressed as mean (data points), median (horizontal lines), interquartile ranges (bars), and 10th and 90th percentiles (error bars). P values represent differences between subgroups with and without myocardial dysfunction. The Journal of Thoracic and Cardiovascular Surgery 2002 124, 811-820DOI: (10.1067/mtc.2002.122308) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions

Fig. 4 IL-8 levels related to presence (white bars, n = 11) and absence (shaded bars, n = 52) of myocardial dysfunction after CPB in 63 patients. Values expressed as mean (data points), median (horizontal lines), interquartile ranges (bars), and 10th and 90th percentiles (error bars). P values represent differences between subgroups with and without myocardial dysfunction. The Journal of Thoracic and Cardiovascular Surgery 2002 124, 811-820DOI: (10.1067/mtc.2002.122308) Copyright © 2002 American Association for Thoracic Surgery Terms and Conditions