Effects of intracoronary shunts on coronary endothelial coating in the human beating heart Herbert B Hangler, MD, Kristian Pfaller, PhD, Elfriede Ruttmann,

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Presentation transcript:

Effects of intracoronary shunts on coronary endothelial coating in the human beating heart Herbert B Hangler, MD, Kristian Pfaller, PhD, Elfriede Ruttmann, MD, Daniel Hoefer, MD, Thomas Schachner, MD, Guenther Laufer, MD, Herwig Antretter, MD The Annals of Thoracic Surgery Volume 77, Issue 3, Pages 776-780 (March 2004) DOI: 10.1016/j.athoracsur.2003.08.052

Fig 1 (A) Control specimen from patient 2; scanning electron micrograph depicts an overview of a coronary artery cut into half longitudinally after pressure fixation with an intact endothelial surface. (B) Inset, higher magnification with tight endothelial cell attachment completely covering the vascular surface, corresponding to a grade 0 classification. The Annals of Thoracic Surgery 2004 77, 776-780DOI: (10.1016/j.athoracsur.2003.08.052)

Fig 2 (A) Dehiscent intercellular junctions and detachment of endothelial cells (grade 2: minor endothelial injury). (B) Inset, higher magnification. (# = endothelial cell.) The Annals of Thoracic Surgery 2004 77, 776-780DOI: (10.1016/j.athoracsur.2003.08.052)

Fig 3 (A) Focal endothelial denudation after vessel loop occlusion. Note denuded area (*), with subendothelial tissue exposed (grade 3). (# = remnant endothelial cells.) (B) Inset, higher magnification. The Annals of Thoracic Surgery 2004 77, 776-780DOI: (10.1016/j.athoracsur.2003.08.052)

Fig 4 (A) Severe endothelial injury (grade 4) after shunt (outer diameter, 2.5 mm) insertion in vessel from patient 2. Note denuded area (*), with subendothelial tissue exposed. (# = remnant endothelial cells.) (B) Inset, higher magnification. The Annals of Thoracic Surgery 2004 77, 776-780DOI: (10.1016/j.athoracsur.2003.08.052)