3D-histopathological grading of articular cartilage using contrast-enhanced high- resolution micro-CT H. Gahunia, S. Karhula, T. Ylitalo, E. Hæggström,

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3D-histopathological grading of articular cartilage using contrast-enhanced high- resolution micro-CT H. Gahunia, S. Karhula, T. Ylitalo, E. Hæggström, K.P. Pritzker, S. Saarakkala, H.J. Nieminen Osteoarthritis and Cartilage Volume 24, Pages S277-S278 (April 2016) DOI: 10.1016/j.joca.2016.01.516 Copyright © 2016 Terms and Conditions

Fig. 1. Exemplary μCT images of osteochondral plugs (left) with different degeneration (normal/mild/ moderate/severe) and adjacent tissue (right) (spacing indicated between the slices in μm). Pathologically most important features have been highlighted with yellow letters. The μCT grade ranges from 0 (normal) to 44 (extremely severe). μCT was capable of providing a sufficient contrast and resolution to permit 3D- histopathological grading of human osteochondral samples. Osteoarthritis and Cartilage 2016 24, S277-S278DOI: (10.1016/j.joca.2016.01.516) Copyright © 2016 Terms and Conditions