Biomarkers: A Basic Glossary

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Presentation transcript:

Biomarkers: A Basic Glossary Ramachandran S. Vasan. Circulation 2006;113:2335-2362

Desirable Features of Biomarkers of Atherosclerotic CVD R. S. Vasan. Circulation 2006;113:2335-2362

Measures of biomarker test performance Ramachandran S. Vasan. Circulation 2006;113:2335-2362

Approaches to defining “abnormal” biomarker values FN indicates false-negative; FP, false-positive; TN, true-negative; TP, true-positive; Pts, patients; and F/U, follow-up Ramachandran S. Vasan. Circulation 2006;113:2335-2362

Sources of Biomarker Variability R. S. Vasan. Circulation 2006;113:2335-2362

Techniques Available for Biomarker Development Ramachandran S. Vasan. Circulation 2006;113:2335-2362

Brief “Omics” Glossary R. S. Vasan. Circulation 2006;113:2335-2362

Glossary of Terms for Select Techniques Used in the OMICs Toolbox R. S. Vasan. Circulation 2006;113:2335-2362

Five phases of biomarker development: from discovery to delivery Ramachandran S. Vasan. Circulation 2006;113:2335-2362

Some Key Questions to Ask Before Using a New Biomarker in Practice Ramachandran S. Vasan. Circulation 2006;113:2335-2362

Biomarkers for Identifying the Vulnerable Patient R. S. Vasan. Circulation 2006;113:2335-2362

Biomarkers of acute coronary syndromes Ramachandran S. Vasan. Circulation 2006;113:2335-2362

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