Joseph H. Rapp, MD, Kelsy Hollenbeck, BS, Xian Mang Pan, MD

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An experimental model of lacunar infarction: Embolization of microthrombi Joseph H. Rapp, MD, Kelsy Hollenbeck, BS, Xian Mang Pan, MD Journal of Vascular Surgery Volume 48, Issue 1, Pages 196-200 (July 2008) DOI: 10.1016/j.jvs.2008.01.038 Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 1 Three photomicrografts of immunohistochemistry staining of an area of infarction after injection of microthrombi. A, Infarction indicated by a lack of neuronal cell death (NeuN) staining. B, Activated microglia shown with staining for activated microglia (CD11b). C, Activated astrocytes (GFAP) staining showing activation of astrocytes in the area. Journal of Vascular Surgery 2008 48, 196-200DOI: (10.1016/j.jvs.2008.01.038) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 2 Intraluminal thrombus in vessel leading to an area of infarction after injection of microthrombi. Journal of Vascular Surgery 2008 48, 196-200DOI: (10.1016/j.jvs.2008.01.038) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 3 Two vessels with circumferential perivascular staining for albumin indicating disruption of the blood brain barrier after injection of cholesterol crystals. Journal of Vascular Surgery 2008 48, 196-200DOI: (10.1016/j.jvs.2008.01.038) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions