Patient characteristics are important determinants of neurodevelopmental outcome at one year of age after neonatal and infant cardiac surgery J. William.

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Presentation transcript:

Patient characteristics are important determinants of neurodevelopmental outcome at one year of age after neonatal and infant cardiac surgery J. William Gaynor, MD, Gil Wernovsky, MD, Gail P. Jarvik, MD, PhD, Judy Bernbaum, MD, Marsha Gerdes, PhD, Elaine Zackai, MD, Alex S. Nord, BA, Robert R. Clancy, MD, Susan C. Nicolson, MD, Thomas L. Spray, MD The Journal of Thoracic and Cardiovascular Surgery Volume 133, Issue 5, Pages 1344-1353.e3 (May 2007) DOI: 10.1016/j.jtcvs.2006.10.087 Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Bar graph showing use and duration of DHCA. The x-axis is DHCA duration in 10-minute increments. The y-axis is number of patients. DHCA, deep hypothermic circulatory arrest. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 1344-1353.e3DOI: (10.1016/j.jtcvs.2006.10.087) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Bar graph showing distribution of MDI and PDI scores. The x-axis is MDI/PDI score in 10-point increments. The y-axis is number of patients. In the general population, MDI and PDI scores are normally distributed with a mean of 100 and a standard deviation of 15. In this cohort, the distribution is shifted to the left, indicating worse performance. The PDI is more severely affected than the MDI. MDI, Mental Developmental Index; PDI, Psychomotor Developmental Index. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 1344-1353.e3DOI: (10.1016/j.jtcvs.2006.10.087) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 A, X-Y plot showing MDI and PDI scores for 111 patients with no risk factors (low birth weight, genetic syndrome, or APOE ϵ2 allele). The x-axis is the MDI score and the y-axis is the PDI score. B, X-Y plot showing MDI and PDI scores for 77 patients with one or more risk factors (low birth weight, genetic syndrome, or APOE ϵ2 allele). The x-axis is the MDI score and the y-axis is the PDI score. The number of patient with low scores on both measures is increased compared with patients with no risk factors (A). BW, Birth weight; APOE, apolipoprotein E; MDI, Mental Developmental Index; PDI, Psychomotor Developmental Index. The Journal of Thoracic and Cardiovascular Surgery 2007 133, 1344-1353.e3DOI: (10.1016/j.jtcvs.2006.10.087) Copyright © 2007 The American Association for Thoracic Surgery Terms and Conditions