A myriad of responses The Lancet Volume 358, (December 2001)

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Presentation transcript:

A myriad of responses The Lancet Volume 358, (December 2001) Charles T Esmon, PhD The Lancet Volume 358, (December 2001) DOI: 10.1016/S0140-6736(01)07073-8 Copyright © 2001 Elsevier Ltd Terms and Conditions

Figure Severe sepsis induces release of cytokines, oxidants, and proteases from leucocytes, injuring the vessel, triggering clotting, and inhibiting the protein C pathway (A). APC limits many of these events, protecting the vessels and organs from injury (B). The Lancet 2001 358, DOI: (10.1016/S0140-6736(01)07073-8) Copyright © 2001 Elsevier Ltd Terms and Conditions

The Lancet 2001 358, DOI: (10.1016/S0140-6736(01)07073-8) Copyright © 2001 Elsevier Ltd Terms and Conditions