Human oocytes containing large cytoplasmic vacuoles can result in pregnancy and viable offspring  Péter Fancsovits, Ákos Murber, Zsuzsa Tóthne Gilán,

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Human oocytes containing large cytoplasmic vacuoles can result in pregnancy and viable offspring  Péter Fancsovits, Ákos Murber, Zsuzsa Tóthne Gilán, János Rigó, János Urbancsek  Reproductive BioMedicine Online  Volume 23, Issue 4, Pages 513-516 (October 2011) DOI: 10.1016/j.rbmo.2011.06.008 Copyright © 2011 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Fertilization and cleavage of oocytes showing one (A and B) or multiple (C) large vacuoles and extremely thin zona pellucida. Oocytes 1 and 2 had normal (2PN) fertilization (D and E) while oocyte 3 resulted in 1PN fertilization (F). Embryos with two (G and H) or four (I) blastomeres were transferred and resulted in singleton pregnancies. mv=multiple vacuoles; v=vacuole; 1PN=one pronucleus; 2PN=two pronuclei. Reproductive BioMedicine Online 2011 23, 513-516DOI: (10.1016/j.rbmo.2011.06.008) Copyright © 2011 Reproductive Healthcare Ltd. Terms and Conditions

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