Another Twist in Helix C and a Missing Pocket

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Another Twist in Helix C and a Missing Pocket Elizabeth J Goldsmith, Chung-I Chang Structure Volume 10, Issue 7, Pages 888-889 (July 2002) DOI: 10.1016/S0969-2126(02)00798-0

Figure 1 The Structure of PKA (PDB File 1ATP) Highlighted in gray are the elements missing in the structure of PKB. The residues corresponding to helix B and C were present in the crystal but not the electron density. The activation loop, labeled A loop, is also disordered. The hydrophobic motif and Ser 474 not present in the construct crystallized. Structure 2002 10, 888-889DOI: (10.1016/S0969-2126(02)00798-0)