Ana Cobo, Ph. D. , Juan A. García-Velasco, M. D. , Aila Coello, Ph. D

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Presentation transcript:

Oocyte vitrification as an efficient option for elective fertility preservation Ana Cobo, Ph.D., Juan A. García-Velasco, M.D., Aila Coello, Ph.D., Javier Domingo, M.D., Antonio Pellicer, M.D., José Remohí, M.D. Fertility and Sterility Volume 105, Issue 3, Pages 755-764.e8 (March 2016) DOI: 10.1016/j.fertnstert.2015.11.027 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Distribution of retrieved and vitrified metaphase II (MII) oocytes according to women's ages (years). Different superscripts indicate statistical differences between groups (P<.05). Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Kaplan-Meier plotting of the cumulative live birth rates (CLBR) of at least one baby, depending on the total number of consumed oocytes and categorized by age (≤35 y and ≥36 y). Overall comparisons: log rank (Mantel-Cox); P=.003; Tarone-Ware; P=.011. The table shows the CLBRs and 95% confidence intervals (CsI) when 5–15 oocytes were consumed, according to age. Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Elective fertility preservation (FP) trends regarding the total number of oocyte vitrifications (vit.) for other reasons in our group. The plotting shows the total number of elective FP (EFP) cycles. ∗All of the metaphase II (MII) vitrification cycles at all clinics involved. ∗∗Percentage of EFP cycles among the total MII vitrification cycles. Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Distribution of elective fertility preservation (FP) cycles. Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 3 Marital status, sexual orientation, and level of education of women undergoing fertility preservation. Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 4 Distribution of ages at vitrification. (A) Elective fertility preservation (EFP) due to age. (B) EFP because of an associated medical condition. Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 5 Distribution of patients when returning according to age at vitrification and the mean storage time. (A) Elective fertility preservation (EFP) due to age. (B) EFP because of an associated medical condition. Fertility and Sterility 2016 105, 755-764.e8DOI: (10.1016/j.fertnstert.2015.11.027) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions