Anaphylaxis fatalities and admissions in Australia Woei Kang Liew, MBBS, MRCPCH, FAMS, Elizabeth Williamson, MSc, PhD, Mimi L.K. Tang, MBBS, PhD, FRACP, FRCPA  Journal of Allergy and Clinical Immunology  Volume 123, Issue 2, Pages 434-442 (February 2009) DOI: 10.1016/j.jaci.2008.10.049 Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Causes of anaphylaxis deaths. There were 112 deaths between 1997 and 2005 in Australia. Causes are shown. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Anaphylaxis fatalities. A, Absolute number of anaphylaxis deaths by cause and age group. B, Anaphylaxis death rates by cause and age group. All but 1 food-induced anaphylaxis death occurred in the 10- to 35-year age groups (1 death at 8 years), most insect sting–induced anaphylaxis deaths occurred between 35 and 84 years, and most drug-induced induced anaphylaxis deaths occurred between 60 and 85 years. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Food-induced anaphylaxis admissions between 1994 and 2005 categorized by age group and sex. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Causes of drug-induced and probable drug-induced anaphylaxis fatalities. There were 64 deaths between 1997 and 2005 in Australia. Causes are shown. NSAIDs, Nonsteroidal anti-inflammatory drugs. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 5 Drug-induced anaphylaxis admissions from 1998 to 2005 categorized by age group and sex. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 6 Time trends for food-induced and non–food–induced anaphylaxis admissions and fatalities. A, Time trends for food-induced and non–food-induced anaphylaxis admissions show increasing admission rates. B, Time trends for non–food-induced anaphylaxis admissions categorized by cause. C, Time trends for food-induced and non–food-induced anaphylaxis fatalities have remained stable despite increasing admissions. D, Time trends for non–food-induced anaphylaxis fatalities, with drug-induced and insect sting–induced anaphylaxis deaths shown separately. Data show increasing drug-induced anaphylaxis deaths but decreasing insect sting–induced anaphylaxis deaths. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 6 Time trends for food-induced and non–food–induced anaphylaxis admissions and fatalities. A, Time trends for food-induced and non–food-induced anaphylaxis admissions show increasing admission rates. B, Time trends for non–food-induced anaphylaxis admissions categorized by cause. C, Time trends for food-induced and non–food-induced anaphylaxis fatalities have remained stable despite increasing admissions. D, Time trends for non–food-induced anaphylaxis fatalities, with drug-induced and insect sting–induced anaphylaxis deaths shown separately. Data show increasing drug-induced anaphylaxis deaths but decreasing insect sting–induced anaphylaxis deaths. Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 7 Time trends in food-induced anaphylaxis admissions by age group (1994-2005; A) and causative allergen (1994-1998; B). Journal of Allergy and Clinical Immunology 2009 123, 434-442DOI: (10.1016/j.jaci.2008.10.049) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions