An 8-week open label trial of l-Threonic Acid Magnesium Salt in patients with mild to moderate dementia Tonita E. Wroolie, Kewei Chen, Kathleen T. Watson,

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An 8-week open label trial of l-Threonic Acid Magnesium Salt in patients with mild to moderate dementia Tonita E. Wroolie, Kewei Chen, Kathleen T. Watson, Andrei Iagaru, Ida Sonni, Noelle Snyder, Wendy Lee, Eric M. Reiman, Natalie L. Rasgon Personalized Medicine in Psychiatry Volume 4, Pages 7-12 (December 2017) DOI: 10.1016/j.pmip.2017.07.001 Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 1 Study flow chart. Personalized Medicine in Psychiatry 2017 4, 7-12DOI: (10.1016/j.pmip.2017.07.001) Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 2 Increases and decreases in regional cerebral metabolism with FDG PET pre- and post- l-TAMS treatment (paired t-tests, p<0.05). Personalized Medicine in Psychiatry 2017 4, 7-12DOI: (10.1016/j.pmip.2017.07.001) Copyright © 2017 Elsevier Inc. Terms and Conditions

Fig. 3 Change in mean MMSE over time. Personalized Medicine in Psychiatry 2017 4, 7-12DOI: (10.1016/j.pmip.2017.07.001) Copyright © 2017 Elsevier Inc. Terms and Conditions