Differential Pulmonary Vein Gases Predict Primary Graft Dysfunction

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Differential Pulmonary Vein Gases Predict Primary Graft Dysfunction Phil Botha, MRCS, Dipesh Trivedi, FRCS, Cait P. Searl, FRCA, Paul A. Corris, FRCP, Stephan V.B. Schueler, FRCS, John H. Dark, FETCS  The Annals of Thoracic Surgery  Volume 82, Issue 6, Pages 1998-2002 (December 2006) DOI: 10.1016/j.athoracsur.2006.07.026 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 General correlation between the number of pulmonary veins with partial pressure of oxygen (Po2) less than 300 mm Hg in the donor and the incidence of primary graft dysfunction (PGD; p = 0.01). Only pulmonary vein gases of transplanted lungs were included in the analysis. The Annals of Thoracic Surgery 2006 82, 1998-2002DOI: (10.1016/j.athoracsur.2006.07.026) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Correlation between the number of pulmonary veins with partial pressure of oxygen (Po2) less than 300 mm Hg in the donor and the incidence of primary graft dysfunction (PGD). Separate analysis of single and bilateral lung transplants. Only pulmonary vein gases of transplanted lungs were included in the analysis. (□ = single; ■ = bilateral.) The Annals of Thoracic Surgery 2006 82, 1998-2002DOI: (10.1016/j.athoracsur.2006.07.026) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Scatter plot demonstrating the poor correlation between arterial partial pressure of oxygen to fraction of inspired oxygen Po2/Fio2 ratio at referral and the lowest pulmonary vein gas (PVG) Po2/Fio2 ratio in each transplanted lung. The Annals of Thoracic Surgery 2006 82, 1998-2002DOI: (10.1016/j.athoracsur.2006.07.026) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Scatter plot demonstrating the correlation between the lowest pulmonary vein gas (PVG) Po2/Fio2 ratio and the Po2/Fio2 ratio in the ipsilateral pulmonary vein. Best-fit linear regression with 95% confidence interval. (y = 188.57 + 0.71x; Po2/Fio2 = partial pressure of oxygen to fraction of inspired oxygen.) The Annals of Thoracic Surgery 2006 82, 1998-2002DOI: (10.1016/j.athoracsur.2006.07.026) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions