Role of the endothelium in the vascular effects of vitamin C in rats

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Role of the endothelium in the vascular effects of vitamin C in rats R.R Ettarh, O.A Sofola, S.A Adigun Pathophysiology Volume 9, Issue 2, Pages 97-101 (January 2003) DOI: 10.1016/S0928-4680(02)00077-9

Fig. 1 Concentration–response curves to NA in (A) endothelium-intact and (B) endothelium-denuded aortic rings from control and vitamin C-treated rats. All concentrations represent final bath concentrations. Each point on the graphs represents mean±SEM of 5–7 rings from different animals. *P<0.05 compared with control rats (Student's t-test). Pathophysiology 2003 9, 97-101DOI: (10.1016/S0928-4680(02)00077-9)

Fig. 2 Concentration–response curves to KCl in (A) endothelium-intact and (B) endothelium-denuded aortic rings from control and vitamin C-treated rats. All concentrations represent final bath concentrations. Each point on the graphs represents mean±SEM of 6–9 rings from different animals. *P<0.05 compared with control rats (Student's t-test). Pathophysiology 2003 9, 97-101DOI: (10.1016/S0928-4680(02)00077-9)

Fig. 3 Relaxation response of aortic rings to ACh from control and vitamin C-treated rats. Relaxation responses are expressed as percentage of decrease in submaximal contraction elicited by NA (10−7 mol/l). Each point on the graph represents mean±SEM of 7 rings from different animals. *P<0.05 compared with control rats (Student's t-test). Pathophysiology 2003 9, 97-101DOI: (10.1016/S0928-4680(02)00077-9)

Fig. 4 Relaxation response of aortic rings to sodium SNP from control and vitamin C-treated rats. Relaxation responses are expressed as percentage of decrease in submaximal contraction elicited by NA (10−7 mol/l). Each point on the graph represents mean±SEM of 7 rings from different animals. Pathophysiology 2003 9, 97-101DOI: (10.1016/S0928-4680(02)00077-9)