CC chemokine receptors CCR1 and CCR4 are expressed on airway mast cells in allergic asthma Kawa Amin, PhD, Christer Janson, MD, PhD, Ilkka Harvima, MD,

Slides:

Advertisements

Similar presentations

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Advertisements

Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.

D-dimer: A biomarker for antihistamine-resistant chronic urticaria

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Bronchial subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation Makoto Hoshino, MD, Yutaka Nakamura, MD,

Fatty acids, inflammation, and asthma

Obstructive sleep apnea syndrome and inflammation

Advances in food allergy in 2015

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Ann-Marie M. Schoos, MD, PhD, Jacob D

Airway epithelial cells in asthma

Expression of PD-L1 in mastocytosis

Is 9 more than 2 also in allergic airway inflammation?

Desensitization to Chemotherapeutic Agents

Elevated serum cytokines during human anaphylaxis: Identification of potential mediators of acute allergic reactions Shelley F. Stone, PhD, Claire Cotterell,

Silvana Balzar, MD, Matthew Strand, PhD, Diane Rhodes, PhD, Sally E

Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-γ–inducible protein 10 expression in asthmatic.

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Yuichi Teraki, MD, Aika Sakurai, MD, Seiichi Izaki, MD

The National Biome Initiative: An allergy perspective

Peter M. Wolfgram, MD, David B. Allen, MD

Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA

Mast cell activation syndrome: Proposed diagnostic criteria

Repeated Episodes of Anaphylaxis with Normal Serum Tryptase but Elevated Levels of Urinary Prostaglandin D2 Phillip Lieberman, MD The Journal of Allergy.

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

What are the best outcome measurements for atopic eczema

The Editors' Choice Journal of Allergy and Clinical Immunology

Augmented epithelial endothelin-1 expression in refractory asthma

The role of the mast cell in the pathophysiology of asthma

Ovalbumin content of influenza vaccines

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Biosimilars and drug development in allergic and immunologic diseases

Inflammatory cells, cytokine and chemokine expression in asthma immunocytochemistry and in situ hybridization Qutayba Hamid, MD, PhD, Editor Journal.

Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Claus Bachert, MD, PhD, Cezmi A. Akdis, MD

Update on the role of prostaglandins in allergic lung inflammation: Separating friends from foes, harder than you might think Martin L. Moore, PhD, R.

What is an “eosinophilic phenotype” of asthma?

Liam O’Mahony, PhD, Mübeccel Akdis, MD, PhD, Cezmi A. Akdis, MD

H. William Kelly, PharmD Journal of Allergy and Clinical Immunology

Autophagy: Nobel Prize 2016 and allergy and asthma research

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

Advances in the approach to the patient with food allergy

Lei Wang, MD, PhD, Jesse P. Joad, MD, Caiyun Zhong, MD, PhD, Kent E

New pathways for itching in patients with atopic dermatitis?

Chemokines and their receptors in allergic disease

The gastrointestinal tract is critical to the pathogenesis of acute HIV-1 infection Saurabh Mehandru, MD, Klara Tenner-Racz, MD, Paul Racz, MD, PhD, Martin.

Correlation between CCL26 production by human bronchial epithelial cells and airway eosinophils: Involvement in patients with severe eosinophilic asthma

Risk of oral food challenges

Benjamin Chaigne, MD, Hervé Watier, MD, PhD

Martin Brasholt, MD, Florent Baty, PhD, Hans Bisgaard, MD, DMSci

Long-term pathologic consequences of acute irritant-induced asthma

Nasal inflammatory mediators and specific IgE production after nasal challenge with grass pollen in local allergic rhinitis Carmen Rondón, MD, PhD, Javier.

Esophageal eosinophilia caused by milk proteins: From suspicion to evidence based on 2 case reports Soledad Terrados Cepeda, MD, Dario Antolin-Amerigo,

Biju Thomas, MD, Robert Anthony Hirst, PhD, Mina H

Measles and immunomodulation

The Editors' Choice Journal of Allergy and Clinical Immunology

IL-9 and c-Kit+ mast cells in allergic rhinitis during seasonal allergen exposure: Effect of immunotherapy Kayhan T. Nouri-Aria, PhD, FRCPath, Charles.

Macrolide antibiotics and asthma treatment

Asthma: The past, future, environment, and costs

Dendritic cells in nasal mucosa of subjects with different allergic sensitizations Susanne M. Reinartz, MD, Joost van Tongeren, MD, Danielle van Egmond,

Environmental factors and eosinophilic esophagitis

Pulmonary chemokines and their receptors differentiate children with asthma and chronic cough Dominik Hartl, MD, Matthias Griese, MD, Thomas Nicolai,

Effect of codeine on objective measurement of cough in chronic obstructive pulmonary disease Jaclyn Smith, MD, PhD, Emily Owen, MPhil, John Earis, MD,

Natural history of cow’s milk allergy

Differences in airway remodeling between subjects with severe and moderate asthma Carmela Pepe, MD, Susan Foley, MD, Joanne Shannon, MD, Catherine Lemiere,

Primary prevention of asthma and allergy

Itching as a systemic disease

Mast cell–associated alveolar inflammation in patients with atopic uncontrolled asthma Cecilia K. Andersson, PhD, Anders Bergqvist, MSc, Michiko Mori,

Advances in mechanisms of allergic disease in 2016

Presentation transcript:

CC chemokine receptors CCR1 and CCR4 are expressed on airway mast cells in allergic asthma Kawa Amin, PhD, Christer Janson, MD, PhD, Ilkka Harvima, MD, PhD, Per Venge, MD, PhD, Gunnar Nilsson, PhD Journal of Allergy and Clinical Immunology Volume 116, Issue 6, Pages 1383-1386 (December 2005) DOI: 10.1016/j.jaci.2005.08.053 Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 Expression of CCR1 (A) and CCR4 (B) in the airways of patients with allergic asthma. Horizontal bars indicate median values. The numbers of the CCR1 (C) and CCR4 (D) were correlated with tryptase-positive mast cells in patients with allergic asthma. Spearman nonparametric correlation test was used. Journal of Allergy and Clinical Immunology 2005 116, 1383-1386DOI: (10.1016/j.jaci.2005.08.053) Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 2 Serial bronchial biopsy specimens from patients with allergic asthma were stained for CCR1 (A) and tryptase G3 (B), or CCR4 (C) and tryptase (D). Original magnification ×340. The scale bars are 10 μm. Journal of Allergy and Clinical Immunology 2005 116, 1383-1386DOI: (10.1016/j.jaci.2005.08.053) Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions