Endoscopic Submucosal Dissection of Esophageal Squamous Cell Neoplasms Mitsuhiro Fujishiro, Naohisa Yahagi, Naomi Kakushima, Shinya Kodashima, Yosuke Muraki, Satoshi Ono, Nobutake Yamamichi, Ayako Tateishi, Yasuhito Shimizu, Masashi Oka, Keiji Ogura, Takao Kawabe, Masao Ichinose, Masao Omata  Clinical Gastroenterology and Hepatology  Volume 4, Issue 6, Pages 688-694 (June 2006) DOI: 10.1016/j.cgh.2006.03.024 Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 1 ESD for esophageal neoplasms. (A) Chromoendoscopy with iodine staining to demarcate the lesion from the non-neoplastic area. (B) Marking around the lesion. (C) Initial mucosal incision after submucosal injection at the distal margin of the lesion. (D) Mucosal incision after submucosal injection at the proximal margin of the lesion and subsequent submucosal dissection from the proximal end. (E) Artificial ulcer after removal. (F) Complete resection of the lesion in one piece. Clinical Gastroenterology and Hepatology 2006 4, 688-694DOI: (10.1016/j.cgh.2006.03.024) Copyright © 2006 American Gastroenterological Association Terms and Conditions

Figure 2 (A) Flexknife. (B) Tip of the Flexknife used for marking the circumference of the lesion. (C) Tip of the Flexknife used for the mucosal incision and submucosal dissection. (D) The proper esophageal glands observed in the submucosal layer (arrowheads). Clinical Gastroenterology and Hepatology 2006 4, 688-694DOI: (10.1016/j.cgh.2006.03.024) Copyright © 2006 American Gastroenterological Association Terms and Conditions