Volume 119, Issue 4, Pages 895-902 (October 2000) A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease  James Markowitz, Kathy Grancher, Nina Kohn, Martin Lesser, Fredric Daum  Gastroenterology  Volume 119, Issue 4, Pages 895-902 (October 2000) DOI: 10.1053/gast.2000.18144 Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 1 Time (days) off of corticosteroid treatment after initial discontinuation, depicted as a Kaplan–Meier survival curve. ■, 6-MP; ▴, controls. P < 0.0001. Gastroenterology 2000 119, 895-902DOI: (10.1053/gast.2000.18144) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 2 Cumulative prednisone dose (mean ± SD). All subjects who withdrew from the study had their last prednisone doses carried forward to the conclusion of the 18-month study period. ▨ , 6-MP (n = 27); ■, controls (n = 28). *P < 0.02; **P < 0.004. Gastroenterology 2000 119, 895-902DOI: (10.1053/gast.2000.18144) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 3 Cumulative prednisone dose (mean ± SD) actually taken by subjects in both groups from day of entry into the study until completion of the 18-month treatment period or until withdrawal. ▨ , 6-MP (n = 27); ■, controls (n = 28). *P < 0.03; **P < 0.007; ***P < 0.008. Gastroenterology 2000 119, 895-902DOI: (10.1053/gast.2000.18144) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 4 Kaplan–Meier survival curve of relapse-free duration of remission. ■, 6-MP; ▴, controls. P < 0.007. Gastroenterology 2000 119, 895-902DOI: (10.1053/gast.2000.18144) Copyright © 2000 American Gastroenterological Association Terms and Conditions