Limited resection for non–small cell lung cancer: observed local control with implantation of I-125 brachytherapy seeds Winnie Lee, MD, Benedict D.T.

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Presentation transcript:

Limited resection for non–small cell lung cancer: observed local control with implantation of I-125 brachytherapy seeds Winnie Lee, MD, Benedict D.T Daly, MD, Thomas A DiPetrillo, MD, Donna M Morelli, BS, Andrew C Neuschatz, MD, Jody Morr, DO, Mark J Rivard, PhD The Annals of Thoracic Surgery Volume 75, Issue 1, Pages 237-242 (January 2003) DOI: 10.1016/S0003-4975(02)04098-5

Fig 1 Portion of lung in which a wedge resection has been carried out. Each limb of the wedge resection is approximately 6 cm in length. Shown is how two 10-seed strands would be affixed to the margin. The most peripheral seeds are placed directly in the margin, and the deeper portions of the wedge have two strands of seeds affixed to the lung spaced approximately 1 cm apart or 0.5 cm from the resection margin. Simple 3-0 silk sutures are used to hold the strands in place. The Annals of Thoracic Surgery 2003 75, 237-242DOI: (10.1016/S0003-4975(02)04098-5)

Fig 2 Diagram of a three-dimensionally reconstructed brachytherapy dosimetry plan using I-125 seeds. The isodose distribution legend is at upper left, the distance scale is at right (yellow), and the average 1-cm dose distribution for this implant was about 110 Gy. In this plane, locations of some of the seeds are indicated by crossed circles. The Annals of Thoracic Surgery 2003 75, 237-242DOI: (10.1016/S0003-4975(02)04098-5)

Fig 3 Cancer-specific survivals for patients with T1N0 and T2N0 tumors. The Annals of Thoracic Surgery 2003 75, 237-242DOI: (10.1016/S0003-4975(02)04098-5)