Quantitative Computed Tomography Analysis, Airflow Obstruction, and Lung Cancer in the Pittsburgh Lung Screening Study  David O. Wilson, MD, MPH, Joseph.

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Quantitative Computed Tomography Analysis, Airflow Obstruction, and Lung Cancer in the Pittsburgh Lung Screening Study  David O. Wilson, MD, MPH, Joseph K. Leader, PhD, Carl R. Fuhrman, MD, John J. Reilly, MD, Frank C. Sciurba, MD, Joel L. Weissfeld, MD  Journal of Thoracic Oncology  Volume 6, Issue 7, Pages 1200-1205 (July 2011) DOI: 10.1097/JTO.0b013e318219aa93 Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 FEV1 (% predicted) versus small airway lumen perimeter (mm) in cases and controls combined (n = 234). The rank order (Spearman) correlations between FEV1 (% predicted) versus small airway lumen perimeter (mm) are 0.50 in the case group, 0.55 in the control group, and 0.53 in both groups combined. Journal of Thoracic Oncology 2011 6, 1200-1205DOI: (10.1097/JTO.0b013e318219aa93) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Box plots showing lung fraction <−910 HU in cases and controls combined, subgrouped according to visual emphysema. The line segment and plus (+) symbol within each box identify the median and mean, respectively. The lower and upper borders of each box identify the 25th and 75th percentiles, respectively. The lower whisker (lower fence) extends to the minimum observation ≥25th percentile minus 1.5 times the interquartile range. The upper whisker (upper fence) extends to the maximum observation ≤75th percentile plus 1.5 times the interquartile range. No subject had a lung fraction <−910 HU measurement less than the lower fence or greater than the upper fence. Journal of Thoracic Oncology 2011 6, 1200-1205DOI: (10.1097/JTO.0b013e318219aa93) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions