Volume 149, Issue 6, Pages (November 2015)

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Volume 149, Issue 6, Pages 1305-1308 (November 2015) Liver Histology and Clinical Trials for Nonalcoholic Steatohepatitis-Perspectives From 2 Pathologists David E. Kleiner Gastroenterology Volume 149, Issue 6, Pages 1305-1308 (November 2015) DOI: 10.1053/j.gastro.2015.09.015 Copyright © 2015 AGA Institute Terms and Conditions

Figure 1 Variation of severity in steatohepatitis. (A, B) Severe steatohepatitis with many large balloon cells. Arrows indicate Mallory–Denk bodies in ballooned hepatocytes; arrowhead points to inflammation. All fields showed equivalent injury. (C, D) Mild steatohepatitis with rare but distinctive balloon cells. Arrow points to possible Mallory-Denk body; arrowhead points to inflammatory focus. These photos show the worst area of this otherwise minimally involved biopsy. (A, C, scale bar = 100 μm; B, D, scale bar = 20 μm). Gastroenterology 2015 149, 1305-1308DOI: (10.1053/j.gastro.2015.09.015) Copyright © 2015 AGA Institute Terms and Conditions