Redesigning the Architecture of the Base Pair: Toward Biochemical and Biological Function of New Genetic Sets  Andrew T. Krueger, Eric T. Kool  Chemistry.

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Redesigning the Architecture of the Base Pair: Toward Biochemical and Biological Function of New Genetic Sets  Andrew T. Krueger, Eric T. Kool  Chemistry & Biology  Volume 16, Issue 3, Pages 242-248 (March 2009) DOI: 10.1016/j.chembiol.2008.12.004 Copyright © 2009 Elsevier Ltd Terms and Conditions

Figure 1 Examples of Base Pairs Designed to Augment the Natural Genetic Set Their dimensions are close to those of natural Watson-Crick pairs. R represents deoxyribose. Chemistry & Biology 2009 16, 242-248DOI: (10.1016/j.chembiol.2008.12.004) Copyright © 2009 Elsevier Ltd Terms and Conditions

Figure 2 Examples of DNA Base Replacements that Have Been Used for Probing Nucleobase Recognition Mechanisms Chemistry & Biology 2009 16, 242-248DOI: (10.1016/j.chembiol.2008.12.004) Copyright © 2009 Elsevier Ltd Terms and Conditions

Figure 3 Novel Base-Pairing Systems Designed to Form New, Non-Purine-Pyrimidine Genetic Sets All have sizes larger than Watson-Crick pairs. Chemistry & Biology 2009 16, 242-248DOI: (10.1016/j.chembiol.2008.12.004) Copyright © 2009 Elsevier Ltd Terms and Conditions

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