Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension Zhenmin Ni, Shahrooz Bemanian, Salah D. Kivlighn,

Slides:

Advertisements

Similar presentations

A.M. Thompson, T.G. Pickering Kidney International

Advertisements

Volume 66, Issue 1, Pages (July 2004)

Lead exposure raises superoxide and hydrogen peroxide in human endothelial and vascular smooth muscle cells Zhenmin Ni, Stephen Hou, Cyril H. Barton,

Plasma sodium and hypertension

Cyril H. Barton, Zehnmin Ni, Nosratola D. Vaziri Kidney International

Francesco Locatelli, Lucia Del Vecchio, Simeone Andrulli, Sara Colzani

Membranous nephropathy: When and how to treat

Prenatal exposure to nicotine modifies kidney weight and blood pressure in genetically susceptible rats: A case of gene-environment interaction Zdenka.

Volume 61, Issue 3, Pages (March 2002)

Glomerulus number and blood pressure in the Prague hypertensive rat

Volume 63, Issue 4, Pages (April 2003)

Dieter A. Häberle, Wolfgang Biller, Takuyuki Ise, Christian J. Metz

The intrarenal renin-angiotensin system in hypertension

Volume 64, Issue 2, Pages (August 2003)

Nosratola D. Vaziri, Kaihui Liang, Yaoxian Ding Kidney International

Kidney immune cell infiltration and oxidative stress contribute to prenatally programmed hypertension Tyrus Stewart, Flavia F. Jung, Jennifer Manning,

Endothelial-derived vasoactive mediators in polycystic kidney disease

Volume 55, Issue 1, Pages (January 1999)

Volume 76, Issue 3, Pages (August 2009)

Xiuqing Wang, Zhongjie Sun, Robert Cade Kidney International

Volume 74, Issue 3, Pages (August 2008)

Proinflammatory effects of iron sucrose in chronic kidney disease

Volume 81, Issue 3, Pages (February 2012)

Comparative effects of potassium chloride and bicarbonate on thiazide-induced reduction in urinary calcium excretion Lynda A. Frassetto, Eileen Nash,

Volume 61, Issue 2, Pages (February 2002)

Volume 54, Issue 5, Pages (November 1998)

Enlightenment on liver lanthanum exposure

Volume 60, Issue 1, Pages (July 2001)

Hypertension promotes integrin expression and reactive oxygen species generation by circulating leukocytes Choong H. Kim, Nosratola D. Vaziri Kidney.

Up-regulation of kidney NAD(P)H oxidase and calcineurin in SHR: Reversal by lifelong antioxidant supplementation Chang-de Zhan, Ram K. Sindhu, Nosratola.

Volume 68, Issue 6, Pages (December 2005)

Blood pressure targets in hemodialysis patients

Volume 66, Issue 1, Pages (July 2004)

The third World Kidney Day: Looking back and thinking forward

Volume 61, Issue 5, Pages (May 2002)

Oral contraceptive administration aggravates nitric oxide synthesis inhibition-induced high blood pressure in female rats L.A. Olatunji, A.O. Soladoye

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Volume 62, Issue 3, Pages (September 2002)

Presentation of the 2003 Jean Hamburger Award to Robert W. Schrier

Volume 56, Issue 2, Pages (August 1999)

Volume 78, Issue 5, Pages (September 2010)

Kaihui Liang, Nosratola D. Vaziri Kidney International

Neuronal nitric oxide synthase inhibition sensitizes the tubuloglomerular feedback mechanism after volume expansion Russell Brown, Anna Ollerstam, A.

Shannon D. Smith, Marcia A. Wheeler, Marc I. Lorber, Robert M. Weiss

Volume 63, Issue 1, Pages (January 2003)

Circadian regulation of renal function

Volume 69, Issue 5, Pages (March 2006)

Nosratola D. Vaziri, Fariba Oveisi, Yaoxian Ding Kidney International

Volume 71, Issue 9, Pages (May 2007)

Carmine Zoccali, Francesca Mallamaci Kidney International

The course of the remnant kidney model in mice

Phosphate binders on iron basis: A new perspective?

Aldosterone in the development and progression of renal injury

Changbin Qiu, Chris Baylis Kidney International

Nosratola D. Vaziri, M.D., Kaihui Liang Kidney International

Volume 72, Issue 3, Pages (August 2007)

Cyril H. Barton, Zhemin Ni, Nosratola D. Vaziri Kidney International

Volume 68, Issue 5, Pages (November 2005)

Molecular mechanisms of altered cholesterol metabolism in rats with spontaneous focal glomerulosclerosis Nosratola D. Vaziri, Tadashi Sato, Kaihui Liang

Salt sensitivity in genetically hypertensive rats of the Lyon strain

Is it the low-protein diet or simply the salt restriction?

Volume 68, Issue 1, Pages (July 2005)

Volume 62, Issue 5, (November 2002)

Volume 76, Issue 9, Pages (November 2009)

Effect of prenatal dexamethasone on rat renal development

Volume 57, Issue 2, Pages (October 2000)

Volume 65, Issue 2, Pages (February 2004)

Volume 66, Issue 1, Pages (July 2004)

Takuyuki Ise, Ken-ichi Kobayashi, Wolfgang Biller, Dieter A. Häberle

Presentation transcript:

Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension Zhenmin Ni, Shahrooz Bemanian, Salah D. Kivlighn, Nosratola D. Vaziri Kidney International Volume 54, Issue 1, Pages 188-192 (July 1998) DOI: 10.1046/j.1523-1755.1998.00987.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Tail systolic blood pressure in placebo-treated rats exposed to hypobaric hypoxia (▪) and the control animals (★) kept at normal atmospheric pressure for 24days. N = 6 in each group; Kidney International 1998 54, 188-192DOI: (10.1046/j.1523-1755.1998.00987.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Plasma concentration of endothelin (A) and urinary excretion of total nitrates and nitrites (NOx, B) in rats exposed to hypobaric hypoxia (•) and normoxia (♦) for 24days.N = 6 in each group. Kidney International 1998 54, 188-192DOI: (10.1046/j.1523-1755.1998.00987.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Systolic arterial blood pressure in placebo-treated (▪), ET-A/B receptor blocker-treated (♦) and L-arginine-treated (★) rats exposed to hypobaric hypoxia for a 24-day period. A minimum of six animals were included in each group. Kidney International 1998 54, 188-192DOI: (10.1046/j.1523-1755.1998.00987.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 4 Urinary excretion of total nitrates and nitrites (NOx) in placebo-treated (•), L-arginine-treated (★) and ET-A/B receptor blocker-treated (♦) hypoxic groups. A minimum of six animals were included in each group. Kidney International 1998 54, 188-192DOI: (10.1046/j.1523-1755.1998.00987.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 54, 188-192DOI: (10. 1046/j. 1523-1755. 1998 Kidney International 1998 54, 188-192DOI: (10.1046/j.1523-1755.1998.00987.x) Copyright © 1998 International Society of Nephrology Terms and Conditions