CDHR3 gene variation and childhood bronchiolitis

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CDHR3 gene variation and childhood bronchiolitis Anders Husby, MD, Anu Pasanen, MSci, Johannes Waage, MSci, PhD, Astrid Sevelsted, MSci, Hennie Hodemaekers, BSc, Riny Janssen, PhD, Minna K. Karjalainen, PhD, Jakob Stokholm, MD, PhD, Bo L. Chawes, MD, PhD, DMSc, Matti Korppi, MD, PhD, Göran Wennergren, MD, PhD, Andrea Heinzmann, MD, Louis Bont, MD, PhD, Hans Bisgaard, MD, DMSc, Klaus Bønnelykke, MD, PhD Journal of Allergy and Clinical Immunology Volume 140, Issue 5, Pages 1469-1471.e7 (November 2017) DOI: 10.1016/j.jaci.2017.06.044 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Geographical distribution of study populations. Journal of Allergy and Clinical Immunology 2017 140, 1469-1471.e7DOI: (10.1016/j.jaci.2017.06.044) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Age distribution of study populations. Journal of Allergy and Clinical Immunology 2017 140, 1469-1471.e7DOI: (10.1016/j.jaci.2017.06.044) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Forest plot of association of CDHR3 gene variation (rs6967330, A allele) with bronchiolitis overall (A), RSV-positive bronchiolitis (B), RSV-negative bronchiolitis (C), and bronchiolitis overall adjusted for sex (D). Journal of Allergy and Clinical Immunology 2017 140, 1469-1471.e7DOI: (10.1016/j.jaci.2017.06.044) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E4 Graphical illustration of the relationship between CDHR3 gene variation and bronchiolitis subtypes in the present study (top part) and resemblance with clinical bronchiolitis phenotypes suggested in a previously published clustering analysisE10 (bottom part). Journal of Allergy and Clinical Immunology 2017 140, 1469-1471.e7DOI: (10.1016/j.jaci.2017.06.044) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions