Mark J. Russo, MD, MS, Ryan R. Davies, MD, Kimberly N

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Presentation transcript:

Matching High-Risk Recipients With Marginal Donor Hearts Is a Clinically Effective Strategy Mark J. Russo, MD, MS, Ryan R. Davies, MD, Kimberly N. Hong, MHSA, Jonathan M. Chen, MD, Michael Argenziano, MD, Alan Moskowitz, MD, Deborah D. Ascheim, MD, Isaac George, Allan S. Stewart, MD, Mathew Williams, MD, Annetine Gelijns, PhD, Yoshifumi Naka, MD, PhD The Annals of Thoracic Surgery Volume 87, Issue 4, Pages 1066-1071 (April 2009) DOI: 10.1016/j.athoracsur.2008.12.020 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier survival analysis after transplantation by transplant group: ALT (alternate list transplant) = high-risk recipient paired with marginal donor (dash-dotted line); HR:SD = high-risk recipient paired with standard donor (dotted line); SR:MD = standard recipient paired with marginal donor (dashed line); STD = standard recipient paired with standard donor (solid line). The Annals of Thoracic Surgery 2009 87, 1066-1071DOI: (10.1016/j.athoracsur.2008.12.020) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Incidence rate of death by time period and group: ALT (alternate list transplant) = high-risk recipient paired with marginal donor (gray bars); HR:SD = high-risk recipient paired with standard donor (speckled bars); SR:MD = standard recipient paired with marginal donor (slashed bars); STD = standard recipient paired with standard donor (checkered bars). The Annals of Thoracic Surgery 2009 87, 1066-1071DOI: (10.1016/j.athoracsur.2008.12.020) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Transplant hospitalization length of stay and incidence of complications by group: ALT (alternate list transplant) = high-risk recipient paired with marginal donor (gray bars); HR:SD = high-risk recipient paired with standard donor (speckled bars); SR:MD = standard recipient paired with marginal donor (slashed bars); STD = standard recipient paired with standard donor (checkered bars). *p value less than 0.05 when compared with the STD group. The Annals of Thoracic Surgery 2009 87, 1066-1071DOI: (10.1016/j.athoracsur.2008.12.020) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Incidence rates of long-term complications of transplantation by group: ALT (alternate list transplant) = high-risk recipient paired with marginal donor (gray bars); HR:SD = high-risk recipient paired with standard donor (speckled bars); SR:MD = standard recipient paired with marginal donor (slashed bars); STD = standard recipient paired with standard donor (checkered bars). (TCAD = transplant coronary artery disease.) The Annals of Thoracic Surgery 2009 87, 1066-1071DOI: (10.1016/j.athoracsur.2008.12.020) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions