20S proteasome activities

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20S proteasome activities Supplemental Figure 1 A B * LBH589 - + - + HuT102 Mock myr-AKT Annexin-V positive cells (%) LBH589 - + - + HuT102 Mock myr-AKT 37kDa 60kDa 35kDa 47kDa 19/17kDa 22kDa b-actin AKT p-AKT Caspase-3 Caspase-2 RAIDD PIDD Caspase-9 cleaved casp-3 cleaved casp-9 cleaved casp-2 cleaved PIDD 51kDa 32kDa 19kDa 90kDa C control LBH589 SAHA MG132 20S proteasome activities (fold induction) HuT102 K562 KOB KK1 LM-Y1 ST1 D control LBH589 SAHA MG132 HuT102 K562 KK1 ST1 RAIDD mRNA