V. Michelacci, G. Prosseda, A. Maugliani, R. Tozzoli, S. Sanchez, S

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Characterization of an emergent clone of enteroinvasive Escherichia coli circulating in Europe V. Michelacci, G. Prosseda, A. Maugliani, R. Tozzoli, S. Sanchez, S. Herrera-León, T. Dallman, C. Jenkins, A. Caprioli, S. Morabito Clinical Microbiology and Infection Volume 22, Issue 3, Pages 287.e11-287.e19 (March 2016) DOI: 10.1016/j.cmi.2015.10.025 Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Cluster analysis of pulsed-field gel electrophoresis profiles of EIEC strains. EIEC, enteroinvasive Escherichia coli. Clinical Microbiology and Infection 2016 22, 287.e11-287.e19DOI: (10.1016/j.cmi.2015.10.025) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 2 Growth curves of the bacterial strains investigated. Symbols indicate the mean values for five observations ± standard errors. ▪ M90T, □ MG1655, ♦ 4608, ▲ 6.81, ◊ ECOR1, ○ EF432, Δ H142690012. Clinical Microbiology and Infection 2016 22, 287.e11-287.e19DOI: (10.1016/j.cmi.2015.10.025) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 3 Swimming motility assays. Bars indicate average swim diameters (mm) and error bars (± standard errors for three independent experiments). Student's t tests value was p < 0.01 when the swim diameters of all strains were compared with swim diameters of MG1655. Clinical Microbiology and Infection 2016 22, 287.e11-287.e19DOI: (10.1016/j.cmi.2015.10.025) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 4 Proposed pathway for evolution of EIEC O96:H19 from commensal Escherichia coli. EIEC, enteroinvasive E. coli. Clinical Microbiology and Infection 2016 22, 287.e11-287.e19DOI: (10.1016/j.cmi.2015.10.025) Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions