Zeng, Xin; Yin, Biaolin; Hu, Zheng; Liao, Chengzhong; Liu, Jinglei; Li, Shang; Li, Zheng; Nicklaus, Marc C.; Zhou, Guangbiao; Jiang, Sheng. Total synthesis.

Slides:



Advertisements
Similar presentations
Designing an SPR biointerface for transmembrane proteins Heather Ferguson Matthew Linman, Dr. Quan “Jason” Cheng BRITE Research Presentation August 20,
Advertisements

Rob Brown Special Topic – 25/01/112
Volume 9, Issue 3, Pages (November 2014)
Chandrasekhar, S.; Basu, Debjit; Sailu, M.; Kotamraju, S. Novel synthetic route to the tricyclic core of ()-galanthamine. Tetrahedron Letters (2009), 50(34),
Molecular Signatures of Major Depression Na Cai, Simon Chang, Yihan Li, Qibin Li, Jingchu Hu, Jieqin Liang, Li Song, Warren Kretzschmar, Xiangchao Gan,
Experiment 2 pH Determination of pKa and Equivalent Weight.
1 Versatile Synthesis Strategy for Carboxylic Acid-functionalized Upconverting Nanophosphors as Biological Labels Zhigang Chen, Huili Chen, He Hu, Mengxiao.
Substitution Reactions of Carboxylic Acid Derivatives
Chapter 84 Cancer Cell Biology and Angiogenesis
Fruit and Vegetables Postharvest Physiology Lab Beijing December 2004.
Neogenin Regulation of BMP-Induced Canonical Smad Signaling and Endochondral Bone Formation Zheng Zhou, Jianxin Xie, Daehoon Lee, Yu Liu, Jiung Jung, Lijuan.
Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells Wei Li, Xin Li, Tianda Li, Ming-Gui Jiang, Haifeng Wan, Guan-Zheng Luo, Chunjing.
Department of Chemistry Seminar Announcement Date/Time/VenueTitle/Speaker 7 Apr (Thu) 11am – S8 Level 3 Executive Classroom Development of Molecular.
Superoxide Flashes in Single Mitochondria Wang Wang, Huaqiang Fang, Linda Groom, Aiwu Cheng, Wanrui Zhang, Jie Liu, Xianhua Wang, Kaitao Li, Peidong Han,
Encoding of Both Analog- and Digital-like Behavioral Outputs by One C. elegans Interneuron Zhaoyu Li, Jie Liu, Maohua Zheng, X.Z. Shawn Xu Cell Volume.
Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor Xun Xu, Yong Hou, Xuyang Yin, Li Bao, Aifa Tang, Luting.
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer Shunyou Wang, Jing Gao, Qunying Lei, Nora Rozengurt,
Okura Ken; Matsuoka Shigeru; Goto Ryosuke; Inoue Masayuki The twisted side chain of antillatoxin is important for potent toxicity: total synthesis and.
Container Database Management Zheng Liu, Sheng Liu CSE 534:Advanced computer networks.
Figure 14-1 Molecular Biology of the Cell (© Garland Science 2008)
Biomarkers for Early Diagnostic of Mild Cognitive Impairment in Type-2 Diabetes Patients: A Multicentre, Retrospective, Nested Case–Control Study  Zhi-Peng.
Volume 342, Issue 1, Pages (January 2014)
Follicular Cell-Derived Thyroid Cancer in Children
Volume 79, Issue 1, Pages (January 2013)
Helicobacter pylori infection associated with type 2 diabetic nephropathy in patients with dyspeptic symptoms  Fei Zhou, Xiaoqin Zhong, Jingbo Chen, Chunguo.
Accuracy of Magnetically Controlled Capsule Endoscopy, Compared With Conventional Gastroscopy, in Detection of Gastric Diseases  Zhuan Liao, Xi Hou, En-Qiang.
Volume 77, Issue 9, Pages (May 2010)
Chapter 15: Alcohols, Diols, and Ethers
Improved fat transplantation survival by using the conditioned medium of vascular endothelial growth factor transfected human adipose-derived stem cells 
Volume 65, Issue 5, Pages (November 2016)
Carbodiimide Treatment Dramatically Potentiates the Anticalcific Effect of Alpha-Amino Oleic Acid on Glutaraldehyde-Fixed Aortic Wall Tissue  Peter Zilla,
Biomedical Engineering Student
Supplemental Figure 1. Figure legend. Synthesis of 5-Amino-2-hydroxy-benzoic acid 4-(5-thioxo-5H-[1,2]dithiol-3-yl)-phenyl ester (5-ASA-ADT, 4). Reaction.
Treatment of Psoriasis with Mesenchymal Stem Cells
Volume 25, Issue 4, Pages (April 2014)
Zheng Ping, Xu Ji-Wen, Wang Gui-Song, Zhou Hong-Yu, Tian Xin 
دانشگاه آزاد اسلامی واحد زاهدان
CH 3-6: Acid/Base Exchange Reactions (Multistep Reactions)
Unit 6: Acid-Base Applications Lesson 2: Indicators
Observation of electrode lithiation process and interfacial evolution in lithium ion battery by in-situ TEM technique Speaker: Xi Chen Advisor: Dr. Junjie.
Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus  Li Zhou, Ming-Zhe Liu, Qing.
Changing cancer survival in China during 2003–15: a pooled analysis of 17 population- based cancer registries  Hongmei Zeng, PhD, Prof Wanqing Chen, MD,
Bivalent inhibition of human β-tryptase
Volume 74, Issue 6, Pages (December 2018)
Education & Development center
Accuracy of Magnetically Controlled Capsule Endoscopy, Compared With Conventional Gastroscopy, in Detection of Gastric Diseases  Zhuan Liao, Xi Hou, En-Qiang.
Association of the genetic polymorphisms in pre-microRNAs with risk of childhood epilepsy in a Chinese population  Yang Li, Jinqiu Wang, Chunming Jiang,
Association of the CHRNA3 Locus with Lung Cancer Risk and Prognosis in Chinese Han Population  Xiaomin Niu, MD, Zhiwei Chen, MD, PhD, Shengping Shen,
The Annals of Thoracic Surgery
Molecular Therapy - Nucleic Acids
Thoracoscopic Surgery Versus Thoracotomy for Lung Cancer: Short-Term Outcomes of a Randomized Trial  Hao Long, MD, Qunyou Tan, MD, Qingquan Luo, MD, Zheng.
CH 3-5: pH, pKa and Acid/Base Structure
Zheng Wang, Xing-Mao Zhang, Jun-Jie Hu, Zhi-Xiang Zhou 
Epidermal Growth Factor Receptor Mutations and Their Correlation with Gefitinib Therapy in Patients with Non-small Cell Lung Cancer: A Meta-Analysis Based.
A Clinical Risk Model for the Evaluation of Bronchopleural Fistula in Non-Small Cell Lung Cancer After Pneumonectomy  Xue-fei Hu, MD, Liang Duan, MD,
Differentiate the function:    {image} .
Embryonic Fate Mapping Uncovers the Critical Role of microRNAs in the Development of Epidermal γδ T Cells  Yi Yao, Queping Liu, Carly Martin, Congcong.
Biology Standards.
FOXP3 Is an X-Linked Breast Cancer Suppressor Gene and an Important Repressor of the HER-2/ErbB2 Oncogene  Tao Zuo, Lizhong Wang, Carl Morrison, Xing.
Volume 77, Issue 9, Pages (May 2010)
Algebra Substitution a = 3 ; b = 4 and c = -1 2a + c b2 – a2 2b2
Biology of Blood and Marrow Transplantation
Volume 65, Issue 5, Pages (November 2016)
Fig. 1 Strategies for loading LRAs into LCNPs.
Figure 4 DNM1 mutations affect protein levels and self-dimerization (A) HeLa cells were transfected with green fluorescent protein (GFP)-tagged mutant.
Acquired Mechanism of Crizotinib Resistance in NSCLC with MET Exon 14 Skipping  Wei Jin, MD, Benjie Shan, MD, Hu Liu, PhD, Shoubing Zhou, PhD, Wenjuan.
A Maternal Effect on Queen Production in Honeybees
Bivalent inhibition of human β-tryptase
Questions (Clickers) Which is the stronger acid? Acetic acid Phenol
Fig. 4 In situ mapping of human patient breast cancer and stroma.
Presentation transcript:

Zeng, Xin; Yin, Biaolin; Hu, Zheng; Liao, Chengzhong; Liu, Jinglei; Li, Shang; Li, Zheng; Nicklaus, Marc C.; Zhou, Guangbiao; Jiang, Sheng. Total synthesis and biological evaluation of Largazole and derivatives with promising selectivity for cancers cells. Organic Letters (2010), 12(6), 1368-1371.

DIPEA = diisopropylethylamine pKa of conjugate acid = 11

Piperidine = pKa of conjugate acid = 11.24

HOBt = 1-hydroxybenzotriazole HOAt = 1-hydroxy-7-azabenzotriazole

CSA = camphorsulfonic acid

EDC = Ethyl dimethylaminopropyl carbodiimide

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.