TLR2 expression is significantly higher in alveolar epithelium than in nasal epithelium, and correlates with IL-8 secretion. TLR2 expression is significantly.

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Presentation transcript:

TLR2 expression is significantly higher in alveolar epithelium than in nasal epithelium, and correlates with IL-8 secretion. TLR2 expression is significantly higher in alveolar epithelium than in nasal epithelium, and correlates with IL-8 secretion. (A) Comparison of TLR2 expression in primary nasal and alveolar epithelium, in the presence or absence of PGN. *p<0.05, **p<0.01 using the Mann-Whitney U test. (B) Correlation between TLR2 expression and IL-8 secretion in primary cells, in the presence or absence of PGN. Dots represent nasal epithelial cells, grey triangles represent alveolar cells. *p<0.05, **p<0.01 using Spearman's rank correlation coefficient. TLR, Toll-like receptor; IL, interleukin; PGN, peptidoglycan. Olga Lucia Moncayo-Nieto et al. BMJ Open Resp Res 2014;1:e000046 ©2014 by British Thoracic Society