Volume 79, Issue 3, Pages 340-346 (February 2011) Changes in anemia management and hemoglobin levels following revision of a bundling policy to incorporate recombinant human erythropoietin  Takeshi Hasegawa, Jennifer L. Bragg-Gresham, Ronald L. Pisoni, Bruce M. Robinson, Shunichi Fukuhara, Takashi Akiba, Akira Saito, Kiyoshi Kurokawa, Tadao Akizawa  Kidney International  Volume 79, Issue 3, Pages 340-346 (February 2011) DOI: 10.1038/ki.2010.382 Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 1 Distributions of hemoglobin levels by cross-section. Intervals are <8, 8 to <9, 9 to <10, 10 to <11, 11 to <12, 12 to <13, and ≥13 g/dl. Kidney International 2011 79, 340-346DOI: (10.1038/ki.2010.382) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 2 Distributions of recombinant human erythropoietin (rHuEPO) doses by cross-section. Overall percentage of patients prescribed rHuEPO in January 2006 was 81.9% and in January 2007 was 82.2% (P=0.75). Among patients prescribed erythropoietin (EPO), the mean dose was 11.8% lower after bundling (P<0.001). The distribution of rHuEPO dose (as captured by the four categories in the figure) also differed between cross-sections (P<0.001). Kidney International 2011 79, 340-346DOI: (10.1038/ki.2010.382) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 3 Distributions of intravenous (IV) iron doses by cross-section. Overall percentage of patients prescribed IV iron in January 2006 was 31.8% and in January 2007 was 41.2% (P<0.001). Among patients prescribed IV iron, mean doses rose 6mg/month (P=0.15). The distribution of IV iron prescription (as captured by the five categories in the figure) also differed between cross sections (P<0.001). Kidney International 2011 79, 340-346DOI: (10.1038/ki.2010.382) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 4 Distributions of transferrin saturation (TSAT) by cross-section. Intervals are <10, 10 to <20, 20 to <30, 30 to <40, 40 to <50, and ≥50%. Kidney International 2011 79, 340-346DOI: (10.1038/ki.2010.382) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 5 Distributions of ferritin by cross-section. Intervals are <50, 50 to <100, 100 to <200, 200 to <300, 300 to <400, 400 to <500, and ≥500 ng/ml. Kidney International 2011 79, 340-346DOI: (10.1038/ki.2010.382) Copyright © 2011 International Society of Nephrology Terms and Conditions