Chronic GVHD and Pretransplantation Abnormalities in Pulmonary Function Are the Main Determinants Predicting Worsening Pulmonary Function in Long-term.

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Chronic GVHD and Pretransplantation Abnormalities in Pulmonary Function Are the Main Determinants Predicting Worsening Pulmonary Function in Long-term Survivors after Stem Cell Transplantation  Bipin N. Savani, Aldemar Montero, Ramaprasad Srinivasan, Anurag Singh, Aarthi Shenoy, Stephan Mielke, Katayoun Rezvani, Shervin Karimpour, Richard Childs, A. John Barrett  Biology of Blood and Marrow Transplantation  Volume 12, Issue 12, Pages 1261-1269 (December 2006) DOI: 10.1016/j.bbmt.2006.07.016 Copyright © 2006 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Time to a significant decline in pulmonary function (from baseline) in (a) all patients, (b) abnormal pulmonary function (diffusion capacity for carbon monoxide and/or forced expiratory volume in the first second <80% predicted) versus normal pulmonary function before transplantation, (c) present versus absent chronic graft-versus-host disease (cGVHD), and (d) myeloablative (MT) versus nonmyeloablative (NST) stem cell transplantation. Biology of Blood and Marrow Transplantation 2006 12, 1261-1269DOI: (10.1016/j.bbmt.2006.07.016) Copyright © 2006 American Society for Blood and Marrow Transplantation Terms and Conditions

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