Illustration of σ down-regulation in bladder carcinomas.

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Illustration of 14-3-3σ down-regulation in bladder carcinomas. Illustration of 14-3-3σ down-regulation in bladder carcinomas. Magnified sections of representative 2D PAGE gels run with lysates from normal urothelium (cyst 473, cyst 975) and TCCs of various grades and stages (916-1 pTa G1; 865-3 pTa G2; 702 pT2-4 G3; 697 pT1 G3; 1121-1 pT1 G3; 566 pT2-4 G4). Gels were visualized by autoradiography. Arrowheads indicate the position of 14-3-3σ in the various gels. Expression levels of 14-3-3σ are divided into high (H), medium (M), or low (L). José M. A. Moreira et al. Mol Cell Proteomics 2004;3:410-419 © 2004 The American Society for Biochemistry and Molecular Biology