The tissue plasminogen activator and urokinase response in vivo during natural resolution of venous thrombus Andrew D.R. Northeast, MA, FRCS, Kenneth.

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Presentation transcript:

The tissue plasminogen activator and urokinase response in vivo during natural resolution of venous thrombus Andrew D.R. Northeast, MA, FRCS, Kenneth S. Soo, MA, FRCS, Linda G. Bobrow, PhD, FRCPath, Patrick J. Gaffney, PhD, DSc, Kevin G. Burnand, MS, FRCS Journal of Vascular Surgery Volume 22, Issue 5, Pages 573-579 (November 1995) DOI: 10.1016/S0741-5214(95)70041-2 Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Mean thrombus weight (gm ± 95% confidence interval). Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Thrombus plasminogen activator content (mean activity units ± 95% confidence interval). Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Inferior vena cava tissue plasminogen activator content (mean activity units ± 95% confidence interval). Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Inferior vena cava urokinase content (mean activity units ± 95% confidence interval). Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Superior vena cava tissue plasminogen activator content (mean activity units ± 95% confidence interval). Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 6 Femoral vein tissue plasminogen activator content (mean activity units ± 95% confidence interval). Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 7 Thrombus at 14 days in rat vena cava labeled with rat t-PA riboprobe (in situ hybridization) shows strong monocyte and moderate endothelial staining. Journal of Vascular Surgery 1995 22, 573-579DOI: (10.1016/S0741-5214(95)70041-2) Copyright © 1995 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions