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Volume 89, Issue 2, Pages 167-170 (April 1997) MHC Restriction in Three Dimensions: A View of T Cell Receptor/Ligand Interactions Pamela J Bjorkman Cell Volume 89, Issue 2, Pages 167-170 (April 1997) DOI: 10.1016/S0092-8674(00)80195-6

Figure 1 Structure of a TCR Heterodimer CDR1, yellow; CDR2, green; CDR3, red. Rectangular box in (B) corresponds to pink shaded box in Figure 2B. (2C TCR; Garcia et al., 1996.) Cell 1997 89, 167-170DOI: (10.1016/S0092-8674(00)80195-6)

Figure 2 Structures of Class I and Class II MHC Molecules Locations of high points on MHC helices indicated by arrows in (B), (C), (E), and (F). On a ribbon diagram, the high point on the top of the class II α1 domain is not as pronounced as the other high points, but appears more obvious in surface representations that include side chains. Approximate footprint of a TCR (rectangular box; see Figure 1B) indicated in (B). Cell 1997 89, 167-170DOI: (10.1016/S0092-8674(00)80195-6)

Figure 3 Structures of TCR/MHC/Peptide Complexes Only the V domains of the TCRs are shown. CDR1, yellow; CDR2, green; CDR3, red. (A and B) A6/HLA-A2/peptide (Garboczi et al. 1996; coordinates courtesy of Partho Ghosh). (C) 2C/Kb/peptide (Garcia et al. 1996; coordinates courtesy of Chris Garcia). Cell 1997 89, 167-170DOI: (10.1016/S0092-8674(00)80195-6)