Volume 126, Issue 1, Pages (January 2004)

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From: Hepatitis B Virus Strains with Mutations in the Core Promoter in Patients with Fulminant Hepatitis Ann Intern Med. 1995;122(4): doi: /
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Volume 126, Issue 1, Pages 102-110 (January 2004) Hepatitis B virus maintains its pro-oncogenic properties in the case of occult HBV infection  Teresa Pollicino, Giovanni Squadrito, Giovanni Cerenzia, Irene Cacciola, Giuseppina Raffa, Antonio Craxı̀, Fabio Farinati, Gabriele Missale, Antonina Smedile, Claudio Tiribelli, Erica Villa, Giovanni Raimondo  Gastroenterology  Volume 126, Issue 1, Pages 102-110 (January 2004) DOI: 10.1053/j.gastro.2003.10.048

Figure 1 Schematic representation of the study populations. (A) Study group (HBsAg-negative cirrhotic patients with HCC). (B) Control group (HBsAg-negative patients with CLD). Gastroenterology 2004 126, 102-110DOI: (10.1053/j.gastro.2003.10.048)

Figure 2 Expression of the HBV core mRNA in liver tissues of patients with occult HBV infection. (A) Total RNA isolated from tumor (t) and nontumor (nt) liver specimens of 3 individual cases (a, b, and c) was analyzed by reverse-transcription PCR and the use of specific primers for core mRNA expression. (B) β-actin mRNA was amplified as an internal control for the integrity of the RNA and the quantity loaded per lane. (A and B) m, DNA molecular-weight marker (sizes along left margin). (C) Southern blot analysis was performed to confirm the specificity of the results. +, positive control; −, negative control. Gastroenterology 2004 126, 102-110DOI: (10.1053/j.gastro.2003.10.048)