Schematic representation of seven relevant Gln-modulated protein interactions in the HCT-8 human epithelial cell line under CH11 experimental apoptotic.

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binding sites 58 of the 473 unambiguously assigned phosphorylation sites are predicted by Scansite to be sites for binding. 50 of these correspond.

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Schematic representation of seven relevant Gln-modulated protein interactions in the HCT-8 human epithelial cell line under CH11 experimental apoptotic conditions. Schematic representation of seven relevant Gln-modulated protein interactions in the HCT-8 human epithelial cell line under CH11 experimental apoptotic conditions. Up-regulated and down-regulated proteins are indicated with + (red) and − (green), respectively. The interactions are indicated with lines. tAtg5 and tBib indicate truncated forms of the corresponding proteins. ASK1, apoptosis signal-regulating kinase 1; MOMP, mitochondrial outer membrane permeabilization; NLK, nemo-like kinase; TCF, T cell factor; LEF, lymphoid enhancer factor; Casp, caspase; MAPK, mitogen-activated protein kinase; Jnk, c-Jun NH2-terminal kinase. Nicolas Deniel et al. Mol Cell Proteomics 2007;6:1671-1679 © 2007 The American Society for Biochemistry and Molecular Biology