Allergy to furry animals: New insights, diagnostic approaches, and challenges Jon R. Konradsen, MD, PhD, Takao Fujisawa, MD, PhD, Marianne van Hage, MD,

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Presentation transcript:

Allergy to furry animals: New insights, diagnostic approaches, and challenges Jon R. Konradsen, MD, PhD, Takao Fujisawa, MD, PhD, Marianne van Hage, MD, PhD, Gunilla Hedlin, MD, PhD, Christiane Hilger, PhD, Jörg Kleine-Tebbe, MD, Elizabeth C. Matsui, MD, MHS, Graham Roberts, DM, MRCPCH, Eva Rönmark, PhD, Thomas A.E. Platts- Mills, MD, PhD Journal of Allergy and Clinical Immunology Volume 135, Issue 3, Pages 616-625 (March 2015) DOI: 10.1016/j.jaci.2014.08.026 Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 IgE responses to different cat components can be induced through different routes of exposure and are associated with either inhalant symptoms or 2 forms of food allergy. *Cat IgA and other cat proteins carrying alpha-gal are present as minor constituents of cat dander extracts but are better represented in epithelial extracts. **Fel d 4 is a lipocalin that cross-reacts with Can f 6 and Equ c 1. ‡The albumins all cross-react, but the reactivity between cat and pork albumin is the most consistent. Journal of Allergy and Clinical Immunology 2015 135, 616-625DOI: (10.1016/j.jaci.2014.08.026) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions